CDK1
The protein encoded by this gene is a member of the Ser/Thr protein kinase family. This protein is a catalytic subunit of the highly conserved protein kinase complex known as M-phase promoting factor (MPF), which is essential for G1/S and G2/M phase transitions of eukaryotic cell cycle. Mitotic cyclins stably associate with this protein and function as regulatory subunits. The kinase activity of this protein is controlled by cyclin accumulation and destruction through the cell cycle. The phosphorylation and dephosphorylation of this protein also play important regulatory roles in cell cycle control. Alternatively spliced transcript variants encoding different isoforms have been found for this gene.
| Full Name | cyclin dependent kinase 1 |
| Gene ID | Human: 983 Mouse: 12534 Rat: 54237 Monkey: 699269 |
| UniProt ID | Human: P06493 Mouse: P11440 Rat: P39951 |
| Alternative Names | CDC2; CDC28A; P34CDC2;cyclin-dependent kinase 1;cell cycle controller CDC2;cell division control protein 2 homolog;cell division cycle 2, G1 to S and G2 to M;cell division protein kinase 1;p34 protein kinase |
Product List
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mProX™ Human CDK1 Stable Cell Line
[CAT#: S01YF-1123-KX176]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CDK1 Target Family: Kinases/Enzyme Drug Discovery Assays and Products Target Protein Species: Human Host Cell Type: CHO-K1; HEK293
mProX™ Human CDK12 Stable Cell Line
[CAT#: S01YF-1123-KX178]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CDK12 Target Family: Kinases/Enzyme Drug Discovery Assays and Products Target Protein Species: Human Host Cell Type: HCT116; CHO-K1; HEK293
mProX™ Human CDK13 Stable Cell Line
[CAT#: S01YF-1123-KX179]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CDK13 Target Family: Kinases/Enzyme Drug Discovery Assays and Products Target Protein Species: Human Host Cell Type: HCT116; CHO-K1; HEK293
mProX™ Human CDK16 Stable Cell Line
[CAT#: S01YF-1123-KX180]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CDK16 Target Family: Kinases/Enzyme Drug Discovery Assays and Products Target Protein Species: Human Host Cell Type: MDA-MB-231; CHO-K1; HEK293
mProX™ Human CDK17 Stable Cell Line
[CAT#: S01YF-1123-KX181]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CDK17 Target Family: Kinases/Enzyme Drug Discovery Assays and Products Target Protein Species: Human Host Cell Type: CHO-K1; HEK293
mProX™ Human CDK18 Stable Cell Line
[CAT#: S01YF-1123-KX182]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CDK18 Target Family: Kinases/Enzyme Drug Discovery Assays and Products Target Protein Species: Human Host Cell Type: HeLa; CHO-K1; HEK293
mProX™ Human CDK19 Stable Cell Line
[CAT#: S01YF-1123-KX183]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CDK19 Target Family: Kinases/Enzyme Drug Discovery Assays and Products Target Protein Species: Human Host Cell Type: CHO-K1; HEK293
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