Membrane Preparations
A ligand is a chemical that creates a compound with a biomolecule, such as G-protein coupled receptors (GPCRs), which are typically expressed in cellular membranes. Drug development has been transformed by the introduction of membrane ligand binding assays and high-throughput screening. HTS helps automate research and save development time, whereas ligand binding assays allow us to understand how a ligand or a novel synthetic molecule interacts with a target protein and evaluate the force and speed of the interactions. Membrane preparations from Creative Biolabs are quality-assured frozen membranes from cells expressing recombinant or natural receptors. To evaluate receptor density and affinity, each batch of receptor is subjected to rigorous quality control testing.
Click on any link below for further information about our membrane preparations.
GPCR Membrane Preparations
GPCRs are involved in a staggering variety of bodily processes, and better knowledge of these receptors has had a significant impact on modern medicine. In fact, according to research, between one-third and fifty percent of all commercially available medications work by attaching to GPCRs. Creative Biolabs offers quality-assured frozen membranes from cells expressing recombinant or natural receptors for facilitating the study of GPCRs.
Ion Channel Membrane Preparations
Ion channels are integral membrane proteins that cross cell membranes to create a pore through which certain ions can pass at a rate of up to 100 million per second. They are present in almost every form of creature, including human cells as well as viruses, bacteria, plants, and animals. Creative Biolabs offers quality-assured frozen membranes from cells expressing recombinant or natural receptors for facilitating the study of ion channels.
Transporter Membrane Preparations
Membrane transporters facilitate effective cellular metabolism, assist in nutrition sensing, and have been linked to a number of illnesses, including cancer and obesity. Creative Biolabs offers quality-assured frozen membranes from cells expressing recombinant or natural receptors for facilitating the study of transporters.
Immune Checkpoint Membrane Preparations
Immunological checkpoints are crucial for immune control, and inhibiting them on the cell membrane is a viable approach to treating cancer. Creative Biolabs offers quality-assured frozen membranes from cells expressing recombinant or natural receptors for facilitating the study of immune checkpoints.
Kinase Membrane Preparations
Almost every element of cell life is regulated by protein kinases, which have the ability to alter a protein's activity in any way. Enzyme activity as well as other biological processes like transcription and translation can be altered by protein phosphorylation. Creative Biolabs offers quality-assured frozen membranes from cells expressing recombinant or natural receptors for facilitating the study of kinases.
Virology Membrane Preparations
The study of viruses' structure, classification, and evolution, as well as how they attack and use host cells for reproduction, how they interact with the physiology and immunity of the host, the illnesses they cause, how to isolate and culture them, and how to use them in research and therapy, are all topics covered by virology. Creative Biolabs offers quality-assured frozen membranes from cells expressing recombinant or natural receptors for facilitating the study of Virology.
