mProX™ Human CDK1 Stable Cell Line

[CAT#: S01YF-1123-KX176]

Product Category:: Membrane Protein Stable Cell Lines

Subcategory:: Kinase Cell Lines

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Based on this stable cell line, we also provide cell-based in vitro assays to evaluate the effects of your compounds or antibodies.

Sub Cat	Product Name	Target Protein Species	Assay Types
S01YF-1122-KX1056	Magic™ Human CDC2/CycB1 in Vitro Assay	Human	Kinase Assay
S01YF-1122-KX1058	Magic™ Human CDK1/CycA2 in Vitro Assay	Human	Kinase Assay
S01YF-1122-KX1059	Magic™ Human CDK1/CycE1 in Vitro Assay	Human	Kinase Assay

Product Information

Target Protein

CDK1

Target Family

Kinases/Enzyme Drug Discovery Assays and Products

Target Protein Species

Human

Host Cell Type

CHO-K1; HEK293

Target Classification

Kinase Cell Lines

Target Research Area

Cancer Research; Ocular Research

Related Diseases

Polyploidy and Retinoblastoma. Among its related pathways are Regulation of activated PAK-2p34 by proteasome mediated degradation and Loss of Nlp from mitotic centrosomes

Gene ID

983

UniProt ID

P06493

Product Properties

Biosafety Level

Level 1

Activity

Yes

Quantity

10⁶ cells per vial

Applications

Cell division cycle protein 2 homolog, sometimes referred to as cyclin-dependent kinase 1 (CdK1), is a highly conserved protein that acts as a serine/threonine protein kinase and is essential for controlling the cell cycle. Cell cycle progression is triggered by Cdk1 phosphorylation when it is coupled to its cyclin partners. A sharp decrease in Sic1 levels is caused by Cln1,2 and/or Clb5,6-Cdk1 complex activity, which permits coherent S phase entry. Ultimately, spindle assembly and sister chromatid alignment result from the phosphorylation of M cyclins in combination with Cdk1. The customized CDK1 stable cell line can be used in antibody discovery and development, potential drug candidate screening and signaling pathway researches.

Protocols

Please visit our protocols page.

Customer Reviews

chat Rebecca

This human CDK1 cell line has saved us time and resources. Our team is excited to delve deeper into our investigations with this versatile tool. Apr 12 2023

chat Verified Customer

chat Donna

I think this CDK1 KO cell line is better than many similar products already on the market. Nov 17 2022

chat Verified Customer

FAQ

Any questions about our products? Please visit our frequently asked questions page.

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