F2R
A 7-transmembrane receptor called the coagulation factor II receptor controls the thrombotic response. Cleavage by proteolytic enzymes activates the receptor. The G-protein coupled receptor family includes the F2R. F2R is linked to thrombosis and Bernard-Soulier syndrome, among other diseases. Response to increased platelet cytosolic Ca2+ and Platelet Aggregation Inhibitor Pathway, Pharmacodynamics are two of its associated pathways.
| Full Name | Coagulation factor II thrombin receptor |
| Gene ID | Human: 2149 Mouse: 14062 Rat: 25439 Monkey: 707370 |
| UniProt ID | Human: P25116 Mouse: P30558 Rat: P26824 Monkey: A0A2K5C6X5 |
| Alternative Names | TR; HTR; CF2R; PAR1; PAR-1; proteinase-activated receptor 1; F2R; Coagulation factor II thrombin receptor |
Product List
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Magic™ Human F2RL3 CHO-K1 Cell Line, Calcium flux assay
[CAT#: S01YF-1022-KX100]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: F2RL3 Target Family: Protease-activated receptor Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: CHO-K1 Assay Types: Calcium flux assay
Magic™ Human F2R (NM_001992) CHO-K1 Membrane Preparation
[CAT#: S01YF-0722-KX854]
- Product Category:
- Membranes
- Target Protein: PAR1 Target Family: Protease-Activated Target Protein Species: Human Host Cell Type: CHO-K1 Application: GTPγS Assay; Ligand Binding Assay
Magic™ Human F2RL1 CHO-K1/Gα15 Cell Line, Calcium flux assay
[CAT#: S01YF-1022-KX99]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: F2RL1 Target Family: Protease-activated receptor Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: CHO-K1/Gα15 Assay Types: Calcium flux assay
Magic™ Human F2RL1 U2OS Cell Line with BLA (Beta-Lactamase) Reporter, Reporter Assay
[CAT#: S01YF-1222-KX113]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: F2RL1 Target Family: Protease-Activated receptor Target Protein Species: Human Host Cell Type: U2OS Assay Types: Reporter Assay
Magic™ Human F2RL1 U2OS Cell Line, Calcium flux assay; β-arrestin assay
[CAT#: S01YF-0822-KX76]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: F2RL1 Target Family: Proteinase-activated receptors Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: U2OS Assay Types: Calcium flux assay; β-arrestin assay
Magic™ Human F2R (NM_001992) HeLa Membrane Preparation
[CAT#: S01YF-0722-KX855]
- Product Category:
- Membranes
- Target Protein: PAR1 Target Family: Protease-Activated Target Protein Species: Human Host Cell Type: HeLa Application: GTPγS Assay; Ligand Binding Assay
Magic™ Human F2R CHO-K1 Cell Line, β-arrestin assay
[CAT#: S01YF-0822-KX351]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: F2R Target Family: Protease activated Receptors Target Protein Species: Human Protein Tag: Enzyme tag Host Cell Type: CHO-K1 Assay Types: β-arrestin assay
Magic™ Human F2RL1 (AY336105) Chem-1 Membrane Preparation
[CAT#: S01YF-0722-KX1024]
- Product Category:
- Membranes
- Target Protein: PAR2 Target Family: Proteinase-Activated Target Protein Species: Human Host Cell Type: Chem-1 Application: GTPγS Assay; Ligand Binding Assay
Magic™ Human F2RL1 (NM_005242.4) HeLa Membrane Preparation
[CAT#: S01YF-0722-KX856]
- Product Category:
- Membranes
- Target Protein: PAR2 Target Family: Protease-Activated Target Protein Species: Human Protein Tag: FLAG-tag at N-terminus Host Cell Type: HeLa Application: GTPγS Assay; Ligand Binding Assay
Magic™ Human F2RL1 Chem-1 Cell Line, Calcium flux assay
[CAT#: S01YF-0822-KX779]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: F2RL1 Target Family: Proteinase-Activated Receptors Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: Chem-1 Assay Types: Calcium flux assay
Magic™ Human F2RL1 CHO-K1 Cell Line with Aequorin Reporter, Calcium flux assay
[CAT#: S01YF-1222-KX147]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: F2RL1 Target Family: Protease-Activated receptor Target Protein Species: Human Host Cell Type: CHO-K1 Assay Types: Calcium flux assay
Magic™ Human F2RL1 CHO-K1 Cell Line, Calcium flux assay
[CAT#: S01YF-0822-KX355]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: F2RL1 Target Family: Protease activated Receptors Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: CHO-K1 Assay Types: Calcium flux assay
Magic™ Human F2RL1 HEK293 Cell Line, β-arrestin assay
[CAT#: S01YF-0822-KX352]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: F2RL1 Target Family: Protease activated Receptors Target Protein Species: Human Protein Tag: Enzyme tag Host Cell Type: HEK293 Assay Types: β-arrestin assay
Magic™ Human F2RL1 U2OS Cell Line, Internalization assay
[CAT#: S01YF-0822-KX354]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: F2RL1 Target Family: Protease activated Receptors Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: U2OS Assay Types: Internalization assay
Magic™ Human F2RL1 U2OS Cell Line, β-arrestin assay
[CAT#: S01YF-0822-KX353]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: F2RL1 Target Family: Protease activated Receptors Target Protein Species: Human Protein Tag: Enzyme tag Host Cell Type: U2OS Assay Types: β-arrestin assay
Magic™ Human F2RL3 (NM_003950.2) HeLa Membrane Preparation
[CAT#: S01YF-0722-KX857]
- Product Category:
- Membranes
- Target Protein: PAR4 Target Family: Protease-Activated Target Protein Species: Human Protein Tag: FLAG-tag at N-terminus Host Cell Type: HeLa Application: GTPγS Assay; Ligand Binding Assay
Magic™ Human F2RL3 CHO-K1 Cell Line with Aequorin Reporter, Calcium flux assay
[CAT#: S01YF-1222-KX146]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: F2RL3 Target Family: Protease-Activated receptor Target Protein Species: Human Host Cell Type: CHO-K1 Assay Types: Calcium flux assay
Magic™ Human F2RL3 CHO-K1 Cell Line, β-arrestin assay
[CAT#: S01YF-0822-KX356]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: F2RL3 Target Family: Protease activated Receptors Target Protein Species: Human Protein Tag: Enzyme tag Host Cell Type: CHO-K1 Assay Types: β-arrestin assay
Magic™ Human F2RL3 U2OS Cell Line, Internalization assay
[CAT#: S01YF-0822-KX357]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: F2RL3 Target Family: Protease activated Receptors Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: U2OS Assay Types: Internalization assay
Magic™ Human FLAG tagged F2R CHO-K1 Cell Line, Calcium flux assay
[CAT#: S01YF-1022-KX556]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: F2R Target Family: Protease-Activated Target Protein Species: Human Host Cell Type: CHO-K1 Assay Types: Calcium flux assay
Magic™ Human FLAG tagged F2R HeLa Cell Line, Calcium flux assay
[CAT#: S01YF-1022-KX557]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: F2R Target Family: Protease-Activated Target Protein Species: Human Host Cell Type: HeLa Assay Types: Calcium flux assay
Magic™ Human FLAG tagged F2RL1 HeLa Cell Line, Calcium flux assay
[CAT#: S01YF-1022-KX558]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: F2RL1 Target Family: Protease-Activated Target Protein Species: Human Protein Tag: FLAG-tag at N-terminus Host Cell Type: HeLa Assay Types: Calcium flux assay
Magic™ Human FLAG tagged F2RL3 HeLa Cell Line, Calcium flux assay
[CAT#: S01YF-1022-KX559]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: F2RL3 Target Family: Protease-Activated Target Protein Species: Human Protein Tag: FLAG-tag at N-terminus Host Cell Type: HeLa Assay Types: Calcium flux assay
Magic™ mPro Human F2R Cell Line
[CAT#: S01YF-1122-KX50]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: F2R Target Family: Protease-Activated Target Protein Species: Human
mProX™ Human F2RL3 Stable Cell Line
[CAT#: S01YF-0923-KX16]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: F2RL3 Target Family: Protease-activated (Thrombin) Family Target Protein Species: Human Host Cell Type: CHO-K1; HEK293
Magic™ mPro Human F2RL1 Cell Line
[CAT#: S01YF-1122-KX51]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: F2RL1 Target Family: Protease-Activated Target Protein Species: Human
Magic™ mPro Human F2RL3 Cell Line
[CAT#: S01YF-1122-KX52]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: F2RL3 Target Family: Protease-Activated Target Protein Species: Human
mProX™ Human F2R Stable Cell Line
[CAT#: S01YF-0923-KX13]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: F2R Target Family: Protease-activated (Thrombin) Family Target Protein Species: Human Host Cell Type: MDA-MB-231; MCF-7; CHO-K1; HEK293
mProX™ Human F2RL1 Stable Cell Line
[CAT#: S01YF-0923-KX14]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: F2RL1 Target Family: Protease-activated (Thrombin) Family Target Protein Species: Human Host Cell Type: CHO-K1; HEK293
mProX™ Human F2RL2 Stable Cell Line
[CAT#: S01YF-0923-KX15]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: F2RL2 Target Family: Protease-activated (Thrombin) Family Target Protein Species: Human Host Cell Type: CHO-K1; HEK293
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