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F2R

A 7-transmembrane receptor called the coagulation factor II receptor controls the thrombotic response. Cleavage by proteolytic enzymes activates the receptor. The G-protein coupled receptor family includes the F2R. F2R is linked to thrombosis and Bernard-Soulier syndrome, among other diseases. Response to increased platelet cytosolic Ca2+ and Platelet Aggregation Inhibitor Pathway, Pharmacodynamics are two of its associated pathways.

Full Name Coagulation factor II thrombin receptor
Gene ID Human: 2149
Mouse: 14062
Rat: 25439
Monkey: 707370
UniProt ID Human: P25116
Mouse: P30558
Rat: P26824
Monkey: A0A2K5C6X5
Alternative Names TR; HTR; CF2R; PAR1; PAR-1; proteinase-activated receptor 1; F2R; Coagulation factor II thrombin receptor

Product List

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Product Category:
Membrane Protein Stable Cell Lines
Target Protein: F2RL1 Target Family: Protease-Activated receptor Target Protein Species: Human Host Cell Type: CHO-K1 Assay Types: Calcium flux assay
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: F2RL1 Target Family: Protease-activated receptor Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: CHO-K1/Gα15 Assay Types: Calcium flux assay
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: F2RL1 Target Family: Protease-Activated receptor Target Protein Species: Human Host Cell Type: U2OS Assay Types: Reporter Assay
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: F2RL3 Target Family: Protease-Activated receptor Target Protein Species: Human Host Cell Type: CHO-K1 Assay Types: Calcium flux assay
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: F2RL3 Target Family: Protease-activated receptor Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: CHO-K1 Assay Types: Calcium flux assay
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: F2R Target Family: Protease-Activated Target Protein Species: Human Host Cell Type: CHO-K1 Assay Types: Calcium flux assay
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: F2RL3 Target Family: Protease-activated (Thrombin) Family Target Protein Species: Human Host Cell Type: CHO-K1; HEK293
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: F2R Target Family: Protease-Activated Target Protein Species: Human Host Cell Type: HeLa Assay Types: Calcium flux assay
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: F2RL1 Target Family: Protease-Activated Target Protein Species: Human Protein Tag: FLAG-tag at N-terminus Host Cell Type: HeLa Assay Types: Calcium flux assay
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: F2RL3 Target Family: Protease-Activated Target Protein Species: Human Protein Tag: FLAG-tag at N-terminus Host Cell Type: HeLa Assay Types: Calcium flux assay
Magic™ mPro Human F2R Cell Line [CAT#: S01YF-1122-KX50]

Product Category:
Membrane Protein Stable Cell Lines
Target Protein: F2R Target Family: Protease-Activated Target Protein Species: Human
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: F2RL1 Target Family: Protease-Activated Target Protein Species: Human
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: F2RL3 Target Family: Protease-Activated Target Protein Species: Human
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: F2R Target Family: Protease-activated (Thrombin) Family Target Protein Species: Human Host Cell Type: MDA-MB-231; MCF-7; CHO-K1; HEK293
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: F2RL1 Target Family: Protease-activated (Thrombin) Family Target Protein Species: Human Host Cell Type: CHO-K1; HEK293
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: F2RL2 Target Family: Protease-activated (Thrombin) Family Target Protein Species: Human Host Cell Type: CHO-K1; HEK293
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