mProX™ Human F2R Stable Cell Line
[CAT#: S01YF-0923-KX13]
- Product Category:
- Membrane Protein Stable Cell Lines
- Subcategory:
- GPCR Cell Lines
Certificate of Analysis Lookup
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
Made to Order Inquiry
InquiryProduct Information
Target Protein
F2R
Target Family
Protease-activated (Thrombin) Family
Target Protein Species
Human
Host Cell Type
MDA-MB-231; MCF-7; CHO-K1; HEK293
Target Classification
GPCR Cell Lines
Target Research Area
Cardiovascular Research
Related Diseases
Thrombosis; Bernard-Soulier Syndrome
Gene ID
UniProt ID
Product Properties
Biosafety Level
Level 1
Activity
Yes
Quantity
10⁶ cells per vial
Applications
PAR-1 was the first member of the protease-activated receptors family. Not only are all types of blood cells expressed with thrombin-activated PAR-1, but also the epithelium, neurons, astrocytes, and immune cells. In addition, the tumor microenvironment contains mast cells, macrophages, blood vessel myocytes, and ECs (Epithelial Cells) that are associated with cancer. PAR-1 raises thrombin and other growth factor levels in macrophages. Since then, much research has concentrated on the function of PAR-1 in tumor cells' biology as well as on PAR-1 agonists and inhibitors. Recent years have seen a surge in interest in drugs that target PAR-1, which is anticipated to lead to novel clinical treatment concepts. The customized F2R stable cell line can be used in antibody discovery and development, potential drug candidate screening and signaling pathway researches.
Protocols
Please visit our protocols page.
Customer Reviews
Jonathan
The F2R cell line surpassed my expectations in terms of sensitivity and ease of use. It's now an essential tool in our lab, and we plan to continue using it for future projects.
Sep 07 2022
Verified Customer
Caroline
I have been using the F2R cell line for my research, and it has consistently provided reliable results.
Apr 17 2023
Verified Customer
FAQ
Any questions about our products? Please visit our frequently asked questions page.
