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  • mProX™ Human F2RL3 Stable Cell Line

    [CAT#: S01YF-0923-KX16]
    Product Category:
    Membrane Protein Stable Cell Lines
    Subcategory:
    GPCR Cell Lines

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    Host Cell Type:
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    Product Information

    Target Protein
    F2RL3
    Target Family
    Protease-activated (Thrombin) Family
    Target Protein Species
    Human
    Host Cell Type
    CHO-K1; HEK293
    Target Classification
    GPCR Cell Lines
    Target Research Area
    Cancer Research; Inflammation Research; Cardiovascular Research
    Related Diseases
    Asthma; Lung Cancer
    Gene ID
    UniProt ID

    Product Properties

    Biosafety Level
    Level 1
    Activity
    Yes
    Quantity
    10⁶ cells per vial
    Applications
    The F2RL3 gene in humans encodes the protein known as protease-activated receptor 4 (PAR-4), also known as coagulation factor II (thrombin) receptor-like 3. A member of the vast family of 7-transmembrane-region receptors that couple to guanosine-nucleotide-binding proteins is the coagulation factor II (thrombin) receptor-like 3 (F2RL3). Another member of the protease-activated receptor family is F2RL3. The extracellular amino terminus of F2RL3 is cleaved by proteases, which activates the protein. The new amino terminus activates the receptor by acting as a tethered ligand. Thrombin and trypsin both activate F2RL3. The customized F2RL3 stable cell line can be used in antibody discovery and development, potential drug candidate screening and signaling pathway researches.

    Protocols

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    Customer Reviews

    chat Rachel

    mProX™ Human F2RL3 Stable Cell Line is very good! Sep 21 2022

    chat Verified Customer

    chat Christopher

    We are satisfied with this F2RL3 cell line and we will use it in our experimental projects. Mar 21 2023

    chat Verified Customer

    FAQ

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    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR CLINICAL PROCEDURES" For licensing inquiries, please contact
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