mProX™ Human F2RL2 Stable Cell Line

[CAT#: S01YF-0923-KX15]

Product Category:: Membrane Protein Stable Cell Lines

Subcategory:: GPCR Cell Lines

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Based on this stable cell line, we also provide cell-based in vitro assays to evaluate the effects of your compounds or antibodies.

Sub Cat	Product Name	Target Protein Species	Host Cell Type	Assay Types	Inquiry	Datasheet
S01YF-1122-KX843	Magic™ Human F2RL2 in Vitro Calcium Flux Assay	Human	CHO-K1	Calcium Flux Assay

Product Information

Target Protein

F2RL2

Target Family

Protease-activated (Thrombin) Family

Target Protein Species

Human

Host Cell Type

CHO-K1; HEK293

Target Classification

GPCR Cell Lines

Target Research Area

Inflammation Research; Cardiovascular Research

Related Diseases

Achondroplasia; Thrombophlebitis Migrans

Gene ID

2151

UniProt ID

O00254

Product Properties

Biosafety Level

Level 1

Activity

Yes

Quantity

10⁶ cells per vial

Applications

Protease-activated receptor 3 (PAR-3), also known as thrombin receptor-like 2 and coagulation factor II receptor-like 2 (F2RL2), is a protein that is encoded by the F2RL2 gene in humans. The vast family of 7-transmembrane receptors that link to G proteins includes the F2RL2 receptor. Another member of the protease-activated receptor family that is thrombin-activated is F2RL2. The extracellular amino terminus of F2RL2 is cleaved by proteases, which activates the protein. The new amino terminus activates the receptor by acting as a tethered ligand. A cofactor for thrombin's activation of F2RL3 is F2RL2. It is expressed in many tissues and mediates thrombin-triggered phosphoinositide hydrolysis. The customized F2RL2 stable cell line can be used in antibody discovery and development, potential drug candidate screening and signaling pathway researches.

Protocols

Please visit our protocols page.

Customer Reviews

chat Anthony

I purchased the Human F2RL2 Stable Cell Line for high-throughput drug screening. Nov 214 2022

chat Verified Customer

chat Caleb

A very stable F2RL2 cell line, especially as there has not been much variation change during my use. Feb 04 2023

chat Verified Customer

FAQ

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