STK3
This gene encodes a serine/threonine protein kinase activated by proapoptotic molecules indicating the encoded protein functions as a growth suppressor. Cleavage of the protein product by caspase removes the inhibitory C-terminal portion. The N-terminal portion is transported to the nucleus where it homodimerizes to form the active kinase which promotes the condensation of chromatin during apoptosis. Multiple transcript variants encoding different isoforms have been found for this gene.
| Full Name | serine/threonine kinase 3 |
| Gene ID | Human: 6788 Mouse: 56274 Rat: 65189 Monkey: 707425 |
| UniProt ID | Human: Q13188 Mouse: Q9JI10 Rat: O54748 |
| Alternative Names | KRS1; MST2;serine/threonine-protein kinase 3;KB-1458E12.1;MST-2;STE20-like kinase MST2;epididymis secretory sperm binding protein;hippo homolog;mammalian STE20-like protein kinase 2;serine/threonine kinase 3 (STE20 homolog, yeast);serine/threonine kinase 3 (Ste20, yeast homolog);serine/threonine-protein kinase Krs-1 |
Product List
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Magic™ Human MST2(STK3) Assay
[CAT#: S01YF-1222-KX392]
- Product Category:
- Membrane Protein Drug Discovery In Vitro Assays
- Target Protein: MST2(STK3) Target Family: Kinases/Enzyme Target Protein Species: Human Assay Types: Kinase Assay
Magic™ Human NDR1(STK38) Assay
[CAT#: S01YF-1222-KX396]
- Product Category:
- Membrane Protein Drug Discovery In Vitro Assays
- Target Protein: NDR1(STK38) Target Family: Kinases/Enzyme Target Protein Species: Human Assay Types: Kinase Assay
Magic™ Human NDR2(STK38L) Assay
[CAT#: S01YF-1222-KX397]
- Product Category:
- Membrane Protein Drug Discovery In Vitro Assays
- Target Protein: NDR2(STK38L) Target Family: Kinases/Enzyme Target Protein Species: Human Assay Types: Kinase Assay
mProX™ Human STK3 Stable Cell Line
[CAT#: S01YF-1023-PY17]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Family: Kinases/Enzyme Target Protein Species: Human Host Cell Type: HEK293;CHO-K1;MKN28 Assay Types: Biological assays
mProX™ Human STK38 Stable Cell Line
[CAT#: S01YF-1023-PY21]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Family: Kinases/Enzyme Target Protein Species: Human Host Cell Type: HEK293;CHO-K1;ST486 Assay Types: Biological assays
mProX™ Human STK38L Stable Cell Line
[CAT#: S01YF-1023-PY22]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Family: Kinases/Enzyme Target Protein Species: Human Host Cell Type: HEK293;CHO-K1 Assay Types: Biological assays
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