mProX™ Human STK3 Stable Cell Line

[CAT#: S01YF-1023-PY17]

Product Category:: Membrane Protein Stable Cell Lines

Subcategory:: Kinase Cell Lines

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Lot Number

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Based on this stable cell line, we also provide cell-based in vitro assays to evaluate the effects of your compounds or antibodies.

Sub Cat	Product Name	Target Protein Species	Host Cell Type	Assay Types	Inquiry	Datasheet
S01YF-1222-KX392	Magic™ Human MST2(STK3) in Vitro Assay	Human		Kinase Assay

Product Information

Target Family

Kinases/Enzyme

Target Protein Species

Human

Host Cell Type

HEK293;CHO-K1;MKN28

Target Classification

Kinase Cell Lines

Target Research Area

Orphan Receptor Research

Related Diseases

Non-Syndromic X-Linked Intellectual Disability

Gene ID

Human:6788

UniProt ID

Human:Q13188

Product Properties

Biosafety Level

Level 1

Activity

Yes

Quantity

10⁶ cells per vial

Applications

The applications of STK3 include its role as a key modulator of the Hippo signaling pathway to limit tissue growth and proliferation, its involvement in the regulation of prolactin-induced crop epithelial proliferation in pigeons, its association with plateau adaptability in cashmere goats, its promotion of oral squamous cell carcinoma through Ras-MAPK mediated cell cycle progression, and its potential as a druggable target for the treatment of metastatic colorectal cancer through ubiquitination and activation of MST2. These findings suggest that targeting STK3 could be a promising approach for modulating cell growth and combatting cancer.

Protocols

Please visit our protocols page.

Customer Reviews

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FAQ

chat Peyton Brown (Verified Customer)

What is the therapeutic potential of STK3 in cancer? Feb 08 2022

chat Patrick Liam (Creative Biolabs Scientific Support)

STK3 is identified as a therapeutic target for a subset of acute myeloid leukemias (AML), suggesting its role in cancer treatment. Feb 08 2022

chat Peyton Garcia (Verified Customer)

How does STK3/STK4 signaling affect adipocytes? Apr 18 2020

chat Patrick Liam (Creative Biolabs Scientific Support)

STK3 and STK4 are key suppressors of mitochondrial capacity in brown, beige, and white adipose tissues, indicating their role in metabolism and obesity-related disorders. Apr 18 2020

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