PDCD1
Programmed cell death protein 1 (PDCD1) is an immune-inhibitory receptor that is produced on activated T cells and is involved in the control of T-cell functions, including effector CD8+ T cell functions. Additionally, this protein can encourage CD4+ T cells to differentiate into T regulatory cells. Melanomas among other tumor forms express PDCD1, which has been shown to contribute to anti-tumor immunity. Additionally, it has been demonstrated that this protein plays a role in protecting against autoimmunity, but it can also contribute to the inhibition of efficient anti-tumor and anti-microbial immunity.
Full Name | Programmed cell death 1 |
Gene ID | Human: 5133 Mouse: 18566 Rat: 301626 Monkey: 100135775 |
UniProt ID | Human: Q15116 Mouse: Q02242 Rat: D3ZIN8 Monkey: B0LAJ2 |
Alternative Names | PDCD1; PD1; PD-1; CD279; SLEB2; hPD-1; hPD-l; hSLE1; programmed cell death protein 1; programmed cell death 1 protein; protein PD-1; systemic lupus erythematosus susceptibility 2; Programmed cell death 1 |
Product List
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: PD-1 Target Family: Immune Checkpoint Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: CHO-K1 Assay Types: Binding assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: PDCD1 (High) Target Family: Immune Checkpoint Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: CHO-K1 Assay Types: Drug screening and biological assays
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: PDCD1 (Middle) Target Family: Immune Checkpoint Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: CHO-K1 Assay Types: Drug screening and biological assays
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: PDCD1 Target Family: Immune Checkpoint Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: H22 Assay Types: Drug screening and biological assays
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: PDCD1 Target Family: Immune Checkpoint Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: HEK293T Assay Types: Drug screening and biological assays
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: PDCD1 Target Family: Immune Checkpoint Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: HH Assay Types: Drug screening and biological assays
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: PDCD1 Target Family: Immune Checkpoint Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: M07e Assay Types: Drug screening and biological assays
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: PDCD1LG2 Target Family: Immune Checkpoint Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: HEK293T Assay Types: Drug screening and biological assays
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: PDCD1LG2 Target Family: Immune Checkpoint Target Protein Species: Human Host Cell Type: MC-38 Assay Types: Functional assay and biological assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: PD-1 Target Family: Immune Checkpoint Target Protein Species: Mouse Protein Tag: Tag-free Host Cell Type: CHO-K1 Assay Types: Binding assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: PDCD1 Target Family: Immune Checkpoint Target Protein Species: Mouse Protein Tag: Tag-free Host Cell Type: HEK293T Assay Types: Drug screening and biological assays
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: PDCD1 Target Family: Immune Checkpoint Target Protein Species: Rat Protein Tag: Tag-free Host Cell Type: HEK293T Assay Types: Drug screening and biological assays
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Family: Immune Checkpoint Target Protein Species: Human Host Cell Type: HEK293;CHO-K1;H9C2
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Family: Immune Checkpoint Target Protein Species: Human Host Cell Type: HEK293;CHO-K1;KHOS;U2OS
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: PDCD1 Target Family: Immune Checkpoint Target Protein Species: Cyno Protein Tag: Tag-free Host Cell Type: HEK293T Assay Types: Drug screening and biological assays
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: PD-1 Target Family: Immune Checkpoint Target Protein Species: Cynomolgus Protein Tag: Tag-free Host Cell Type: CHO-K1 Assay Types: Binding assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: PD-L2 Target Family: Immune Checkpoint Target Protein Species: Cynomolgus Protein Tag: Tag-free Host Cell Type: CHO-K1 Assay Types: Binding assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: PD-L2 Target Family: Immune Checkpoint Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: CHO-K1 Assay Types: Binding assay