PDCD1
Programmed cell death protein 1 (PDCD1) is an immune-inhibitory receptor that is produced on activated T cells and is involved in the control of T-cell functions, including effector CD8+ T cell functions. Additionally, this protein can encourage CD4+ T cells to differentiate into T regulatory cells. Melanomas among other tumor forms express PDCD1, which has been shown to contribute to anti-tumor immunity. Additionally, it has been demonstrated that this protein plays a role in protecting against autoimmunity, but it can also contribute to the inhibition of efficient anti-tumor and anti-microbial immunity.
| Full Name | Programmed cell death 1 |
| Gene ID | Human: 5133 Mouse: 18566 Rat: 301626 Monkey: 100135775 |
| UniProt ID | Human: Q15116 Mouse: Q02242 Rat: D3ZIN8 Monkey: B0LAJ2 |
| Alternative Names | PDCD1; PD1; PD-1; CD279; SLEB2; hPD-1; hPD-l; hSLE1; programmed cell death protein 1; programmed cell death 1 protein; protein PD-1; systemic lupus erythematosus susceptibility 2; Programmed cell death 1 |
Product List
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mProX™ Human PDCD1 Stable Cell Line
[CAT#: S01YF-1023-PY165]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Family: Immune Checkpoint Target Protein Species: Human Host Cell Type: HEK293;CHO-K1;H9C2
mProX™ Human PDCD1LG2 Stable Cell Line
[CAT#: S01YF-1023-PY184]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Family: Immune Checkpoint Target Protein Species: Human Host Cell Type: HEK293;CHO-K1;KHOS;U2OS
Magic™ Human PDCD1LG2 MC-38 Cell Line
[CAT#: S01YF-0324-KX92]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: PDCD1LG2 Target Family: Immune Checkpoint Target Protein Species: Human Host Cell Type: MC-38 Assay Types: Functional assay and biological assay
Human PDCD1 Membrane Protein Yeast Expression Plasmid
[CAT#: S01YF-1124-KX661]
- Product Category:
- Membrane Protein Tools
- Target Protein: PDCD1 Target Family: Immune Checkpoint Vector: pYE Vector Type: Yeast Expression Vector
Human PDCD1 Membrane Protein Retroviral Expression Plasmid
[CAT#: S01YF-1124-KX1006]
- Product Category:
- Membrane Protein Tools
- Target Protein: PDCD1 Target Family: Immune Checkpoint Vector: pRV Vector Type: Retroviral Expression Vector
Human PDCD1 Membrane Protein LNP Encapsulation mRNA
[CAT#: S01YF-1124-KX316]
- Product Category:
- Membrane Protein Tools
- Target Protein: PDCD1 Target Family: Immune Checkpoint RNA Type: LNP-mRNA Formation: LNP Encapsulation mRNA
Human PDCD1 Membrane Protein Lentivirus
[CAT#: S01YF-1124-KX86]
- Product Category:
- Membrane Protein Tools
- Target Protein: PDCD1 Target Family: Immune Checkpoint
Human PDCD1 Membrane Protein Lentiviral Expression Plasmid
[CAT#: S01YF-1124-KX891]
- Product Category:
- Membrane Protein Tools
- Target Protein: PDCD1 Target Family: Immune Checkpoint Vector: pLV Vector Type: Lentiviral Expression Vector
Human PDCD1 Membrane Protein In Vitro Transcription (IVT) Plasmid
[CAT#: S01YF-1124-KX1121]
- Product Category:
- Membrane Protein Tools
- Target Protein: PDCD1 Target Family: Immune Checkpoint Vector: pIVT Vector Type: In Vitro Transcription (IVT) Vector
Human PDCD1 Membrane Protein In Vitro Transcription (IVT) mRNA
[CAT#: S01YF-1124-KX201]
- Product Category:
- Membrane Protein Tools
- Target Protein: PDCD1 Target Family: Immune Checkpoint RNA Type: IVT mRNA Formation: In Vitro Transcription (IVT) mRNA
Human PDCD1 Membrane Protein Bacterial Expression Plasmid
[CAT#: S01YF-1124-KX776]
- Product Category:
- Membrane Protein Tools
- Target Protein: PDCD1 Target Family: Immune Checkpoint Vector: pBE Vector Type: Bacterial Expression Vector
Human PDCD1 Membrane Protein Insect Expression Plasmid
[CAT#: S01YF-1124-KX546]
- Product Category:
- Membrane Protein Tools
- Target Protein: PDCD1 Target Family: Immune Checkpoint Vector: pIE Vector Type: Insect Expression Vector
Human PDCD1 Membrane Protein Mammalian Transient Expression Plasmid
[CAT#: S01YF-1124-KX431]
- Product Category:
- Membrane Protein Tools
- Target Protein: PDCD1 Target Family: Immune Checkpoint Vector: pME Vector Type: Mammalian Transient Expression Vector
Magic™ Human PDCD1LG2 HEK293T Cell Line
[CAT#: S01YF-0123-KX334]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: PDCD1LG2 Target Family: Immune Checkpoint Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: HEK293T Assay Types: Drug screening and biological assays
Magic™ Human PD-L2 CHO-K1 Cell Line, Binding assay
[CAT#: S01YF-1022-KX165]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: PD-L2 Target Family: Immune Checkpoint Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: CHO-K1 Assay Types: Binding assay
Magic™ Cynomolgus PD-L2 CHO-K1 Cell Line, Binding assay
[CAT#: S01YF-1022-KX166]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: PD-L2 Target Family: Immune Checkpoint Target Protein Species: Cynomolgus Protein Tag: Tag-free Host Cell Type: CHO-K1 Assay Types: Binding assay
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