Human PDCD1 Membrane Protein In Vitro Transcription (IVT) mRNA
[CAT#: S01YF-1124-KX201]
- Product Category:
- Membrane Protein Tools
- Subcategory:
- Membrane Protein mRNA Products
Certificate of Analysis Lookup
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Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
Product Information
Product Overview
This product is a made-to-order IVT mRNA encoding human PDCD1.
Target Protein
PDCD1
Target Protein Species
Human
Target Classificationp
Immune Checkpoint
Target Research Area
Autoimmune Research; Cancer Research; Immunology Research
Related Diseases
Systemic Lupus Erythematosus; Multiple Sclerosis
Target Family
Immune Checkpoint
RNA Type
IVT mRNA
Nucleoside Modification Method
m1Ψ; m5C or specific requirements
Cap
Cap 0; Cap 1 or specific requirements
PolyA Tail (nt)
30 nt; 80 nt; 120 nt or specific requirements
5' UTR
Human globin alpha; 5' UTR seq can be modified according to the specific requirements
Promoter
T7
Tag
Based on specific requirements
Fluorescent Markers
Based on specific requirements
Formation
In Vitro Transcription (IVT) mRNA
Quality Control
OD260/280 (~1.90-2.50)
PASS
Agarose Gel Mobility
PASS
Sequence and Enzyme Digestion
PASS
Product Properties
Application
Drug discovery research and pre-clinical studies
Shipping
Dry Ice
Storage
Aliquot and store at -20°C for long term.
Target
Full Name
Programmed cell death 1
Introduction
Programmed cell death protein 1 (PDCD1) is an immune-inhibitory receptor expressed in activated T cells; it is involved in the regulation of T-cell functions, including those of effector CD8+ T cells. In addition, this protein can also promote the differentiation of CD4+ T cells into T regulatory cells. PDCD1 is expressed in many types of tumors including melanomas, and has demonstrated to play a role in anti-tumor immunity. Moreover, this protein has been shown to be involved in safeguarding against autoimmunity, however, it can also contribute to the inhibition of effective anti-tumor and anti-microbial immunity.
Alternative Names
PDCD1; PD1; PD-1; CD279; SLEB2; hPD-1; hPD-l; hSLE1; programmed cell death protein 1; programmed cell death 1 protein; protein PD-1; systemic lupus erythematosus susceptibility 2; Programmed cell death 1
Gene ID
UniProt ID
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