Human PDCD1 Membrane Protein In Vitro Transcription (IVT) Plasmid
[CAT#: S01YF-1124-KX1121]
- Product Category:
- Membrane Protein Tools
- Subcategory:
- Membrane Protein Plasmids
Certificate of Analysis Lookup
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Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
Product Information
Product Overview
This product is a made-to-order plasmid encoding human PDCD1 for In Vitro Transcription.
Target Protein
PDCD1
Target Protein Species
Human
Target Classification
Immune Checkpoint
Target Research Area
Autoimmune Research; Cancer Research; Immunology Research
Related Diseases
Systemic Lupus Erythematosus; Multiple Sclerosis
Target Family
Immune Checkpoint
Vector
pIVT
Vector Type
In Vitro Transcription (IVT) Vector
Note
Resistance
KanR
Growth Temperature
37°C
Relevant Promoters
T7
Mutation
Based on specific requirements
Expressed Tags
Based on specific requirements (Flag, StrepII, His, etc.)
Product Properties
Applications
In Vitro Transcription
Shipping
Blue Ice
Storage
Aliquot and store at -20°C for long term.
Target
Full Name
Programmed cell death 1
Introduction
Programmed cell death protein 1 (PDCD1) is an immune-inhibitory receptor expressed in activated T cells; it is involved in the regulation of T-cell functions, including those of effector CD8+ T cells. In addition, this protein can also promote the differentiation of CD4+ T cells into T regulatory cells. PDCD1 is expressed in many types of tumors including melanomas, and has demonstrated to play a role in anti-tumor immunity. Moreover, this protein has been shown to be involved in safeguarding against autoimmunity, however, it can also contribute to the inhibition of effective anti-tumor and anti-microbial immunity.
Alternative Names
PDCD1; PD1; PD-1; CD279; SLEB2; hPD-1; hPD-l; hSLE1; programmed cell death protein 1; programmed cell death 1 protein; protein PD-1; systemic lupus erythematosus susceptibility 2; Programmed cell death 1
Gene ID
UniProt ID
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