MAP3K1
The protein encoded by this gene is a serine/threonine kinase and is part of some signal transduction cascades, including the ERK and JNK kinase pathways as well as the NF-kappa-B pathway. The encoded protein is activated by autophosphorylation and requires magnesium as a cofactor in phosphorylating other proteins. This protein has E3 ligase activity conferred by a plant homeodomain (PHD) in its N-terminus and phospho-kinase activity conferred by a kinase domain in its C-terminus
| Full Name | mitogen-activated protein kinase kinase kinase 1 |
| Gene ID | Human: 4214 Mouse: 26401 Rat: 116667 Monkey: 710979 |
| UniProt ID | Human: Q13233 Mouse: P53349 Rat: Q62925 |
| Alternative Names | MEKK; MEKK1; SRXY6; MEKK 1; MAPKKK1;mitogen-activated protein kinase kinase kinase 1;MAP/ERK kinase kinase 1;MAPK/ERK kinase kinase 1;MEK kinase 1;mitogen-activated protein kinase kinase kinase 1, E3 ubiquitin protein ligase |
Product List
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mProX™ Human MAP3K1 Stable Cell Line
[CAT#: S01YF-1123-KX291]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: MAP3K1 Target Family: Kinases/Enzyme Drug Discovery Assays and Products Target Protein Species: Human Host Cell Type: 4T1; CHO-K1; HEK293
mProX™ Human MAP3K10 Stable Cell Line
[CAT#: S01YF-1023-PY6]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Family: Kinases/Enzyme Target Protein Species: Human Host Cell Type: HEK293;CHO-K1;BxPC-3;PANC-1
mProX™ Human MAP3K11 Stable Cell Line
[CAT#: S01YF-1023-PY7]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Family: Kinases/Enzyme Target Protein Species: Human Host Cell Type: HEK293;CHO-K1;SAS
mProX™ Human MAP3K19 Stable Cell Line
[CAT#: S01YF-1023-PY136]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Family: Kinases/Enzyme Target Protein Species: Human Host Cell Type: HEK293;CHO-K1;HeLa
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