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GPR6

It is an orphan receptor that activates cyclic AMP through constitutive G(s) signaling. inhibits the inhibition of myelin development in neurons and encourages neurite expansion. Its associated pathways include Class A/1 (Rhodopsin-like receptors). Sphingosine-1-phosphate receptor activity and G protein-coupled receptor activity are two Gene Ontology (GO) annotations connected to this gene.

Full Name G protein-coupled receptor 6
Gene ID Human: 2830
Mouse: 140741
Rat: 83683
Monkey: 697979
UniProt ID Human: P46095
Mouse: Q6YNI2
Rat: P51651
Monkey: A0A0D9SCA1
Alternative Names G-protein coupled receptor 6; sphingosine 1-phosphate receptor GPR6; GPR6; G protein-coupled receptor 6

Product List

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Product Category:
Membrane Protein Stable Cell Lines
Target Protein: GPR6 Target Family: Class A Orphan Receptors Target Protein Species: Human Protein Tag: Enzyme tag Host Cell Type: CHO-K1 Assay Types: β-arrestin assay
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: GPR6 Target Family: Class A Orphan Receptors Target Protein Species: Human Protein Tag: Enzyme tag Host Cell Type: U2OS Assay Types: β-arrestin assay
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: GPR6 Target Family: Orphan Family Target Protein Species: Mouse Host Cell Type: MGN3-1;CHO-K1;HEK293 Assay Types: Biological assays
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: GPR61 Target Family: Class A Orphan Receptors Target Protein Species: Human Protein Tag: Enzyme tag Host Cell Type: CHO-K1 Assay Types: β-arrestin assay
Product Category:
Membranes
Target Protein: GPR65 Target Family: Proton-Sensing Receptors Target Protein Species: Human Protein Tag: FLAG-tag at N-terminus Host Cell Type: HEK293T Application: GTPγS Assay; Ligand Binding Assay
Product Category:
Membranes
Target Protein: GPR65 Target Family: Proton-Sensing Receptors Target Protein Species: Human Protein Tag: FLAG tag at N-terminus Host Cell Type: HEK293T Application: GTPγS Assay; Ligand Binding Assay
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: GPR65 Target Family: Class A Orphan Receptors Target Protein Species: Human Protein Tag: Enzyme tag Host Cell Type: CHO-K1 Assay Types: β-arrestin assay
Product Category:
Membranes
Target Protein: GPR68 Target Family: Proton-Sensing Receptors Target Protein Species: Human Protein Tag: FLAG-tag at N-terminus Host Cell Type: HEK293T Application: GTPγS Assay; Ligand Binding Assay
Product Category:
Membranes
Target Protein: GPR68 Target Family: Proton-Sensing Receptors Target Protein Species: Human Protein Tag: FLAG tag at N-terminus Host Cell Type: HEK293T Application: GTPγS Assay; Ligand Binding Assay
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: GPR68 Target Family: Orphan Receptors Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: Chem-1 Assay Types: Calcium flux assay
Magic™ Mouse GPR65 cAMP Assay [CAT#: S01YF-1122-KX804]

Product Category:
Membrane Protein Drug Discovery In Vitro Assays
Target Protein: GPR65 Target Family: Orphan Receptor Target Protein Species: Mouse Host Cell Type: 1321N1 Assay Types: cAMP Assay
Magic™ Mouse GPR68 cAMP Assay [CAT#: S01YF-1122-KX808]

Product Category:
Membrane Protein Drug Discovery In Vitro Assays
Target Protein: GPR68 Target Family: Class A orphan receptor Target Protein Species: Mouse Host Cell Type: 1321N1 Assay Types: cAMP Assay
Magic™ Rat GPR65 cAMP Assay [CAT#: S01YF-1122-KX805]

Product Category:
Membrane Protein Drug Discovery In Vitro Assays
Target Protein: GPR65 Target Family: Orphan Receptor Target Protein Species: Rat Host Cell Type: 1321N1 Assay Types: cAMP Assay
Magic™ Rat GPR68 cAMP Assay [CAT#: S01YF-1122-KX809]

Product Category:
Membrane Protein Drug Discovery In Vitro Assays
Target Protein: GPR68 Target Family: Class A orphan receptor Target Protein Species: Rat Host Cell Type: 1321N1 Assay Types: cAMP Assay
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: GPR61 Target Family: Orphan Family Target Protein Species: Mouse Host Cell Type: Neuro2A;CHO-K1;HEK293 Assay Types: Biological assays
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: GPR68 Target Family: Class A orphan receptor Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: CHO-K1/Gα15 Assay Types: Calcium flux assay
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: GPR68 Target Family: Proton-Sensing Receptors Target Protein Species: Human Protein Tag: FLAG-tag at N-terminus Host Cell Type: HEK293T Assay Types: Calcium flux assay
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: GPR68; ARRB2 Target Family: Proton-Sensing Receptors Target Protein Species: Human Protein Tag: FLAG-tag at N-terminus Host Cell Type: HEK293T Assay Types: β-Arrestin Assay
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: GPR65 Target Family: Proton-Sensing Receptors Target Protein Species: Human Protein Tag: FLAG-tag at N-terminus Host Cell Type: HEK293T Assay Types: cAMP assay
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: GPR65; ARRB2 Target Family: Proton-Sensing Receptors Target Protein Species: Human Protein Tag: FLAG-tag at N-terminus Host Cell Type: HEK293T Assay Types: β-Arrestin Assay
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: GPR68 Target Family: SPC/LPC/Proton-sensor Family Target Protein Species: Human Host Cell Type: Caco-2; CHO-K1; HEK293
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: GPR65 Target Family: Orphan Family Target Protein Species: Human Host Cell Type: HeLa;CHO-K1;HEK293 Assay Types: Biological assays
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