GPR6
It is an orphan receptor that activates cyclic AMP through constitutive G(s) signaling. inhibits the inhibition of myelin development in neurons and encourages neurite expansion. Its associated pathways include Class A/1 (Rhodopsin-like receptors). Sphingosine-1-phosphate receptor activity and G protein-coupled receptor activity are two Gene Ontology (GO) annotations connected to this gene.
Full Name | G protein-coupled receptor 6 |
Gene ID | Human: 2830 Mouse: 140741 Rat: 83683 Monkey: 697979 |
UniProt ID | Human: P46095 Mouse: Q6YNI2 Rat: P51651 Monkey: A0A0D9SCA1 |
Alternative Names | G-protein coupled receptor 6; sphingosine 1-phosphate receptor GPR6; GPR6; G protein-coupled receptor 6 |
Product List
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: GPR6 Target Family: Class A Orphan Receptors Target Protein Species: Human Protein Tag: Enzyme tag Host Cell Type: CHO-K1 Assay Types: β-arrestin assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: GPR6 Target Family: Class A Orphan Receptors Target Protein Species: Human Protein Tag: Enzyme tag Host Cell Type: U2OS Assay Types: β-arrestin assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: GPR6 Target Family: Orphan Family Target Protein Species: Mouse Host Cell Type: MGN3-1;CHO-K1;HEK293 Assay Types: Biological assays
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: GPR61 Target Family: Class A Orphan Receptors Target Protein Species: Human Protein Tag: Enzyme tag Host Cell Type: CHO-K1 Assay Types: β-arrestin assay
- Product Category:
- Membranes
- Target Protein: GPR65 Target Family: Proton-Sensing Receptors Target Protein Species: Human Protein Tag: FLAG-tag at N-terminus Host Cell Type: HEK293T Application: GTPγS Assay; Ligand Binding Assay
- Product Category:
- Membranes
- Target Protein: GPR65 Target Family: Proton-Sensing Receptors Target Protein Species: Human Protein Tag: FLAG tag at N-terminus Host Cell Type: HEK293T Application: GTPγS Assay; Ligand Binding Assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: GPR65 Target Family: Class A Orphan Receptors Target Protein Species: Human Protein Tag: Enzyme tag Host Cell Type: CHO-K1 Assay Types: β-arrestin assay
- Product Category:
- Membranes
- Target Protein: GPR68 Target Family: Proton-Sensing Receptors Target Protein Species: Human Protein Tag: FLAG-tag at N-terminus Host Cell Type: HEK293T Application: GTPγS Assay; Ligand Binding Assay
- Product Category:
- Membranes
- Target Protein: GPR68 Target Family: Proton-Sensing Receptors Target Protein Species: Human Protein Tag: FLAG tag at N-terminus Host Cell Type: HEK293T Application: GTPγS Assay; Ligand Binding Assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: GPR68 Target Family: Orphan Receptors Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: Chem-1 Assay Types: Calcium flux assay
- Product Category:
- Membrane Protein Drug Discovery In Vitro Assays
- Target Protein: GPR65 Target Family: Orphan Receptor Target Protein Species: Mouse Host Cell Type: 1321N1 Assay Types: cAMP Assay
- Product Category:
- Membrane Protein Drug Discovery In Vitro Assays
- Target Protein: GPR68 Target Family: Class A orphan receptor Target Protein Species: Mouse Host Cell Type: 1321N1 Assay Types: cAMP Assay
- Product Category:
- Membrane Protein Drug Discovery In Vitro Assays
- Target Protein: GPR65 Target Family: Orphan Receptor Target Protein Species: Rat Host Cell Type: 1321N1 Assay Types: cAMP Assay
- Product Category:
- Membrane Protein Drug Discovery In Vitro Assays
- Target Protein: GPR68 Target Family: Class A orphan receptor Target Protein Species: Rat Host Cell Type: 1321N1 Assay Types: cAMP Assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: GPR61 Target Family: Orphan Family Target Protein Species: Mouse Host Cell Type: Neuro2A;CHO-K1;HEK293 Assay Types: Biological assays
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: GPR68 Target Family: Class A orphan receptor Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: CHO-K1/Gα15 Assay Types: Calcium flux assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: GPR68 Target Family: Proton-Sensing Receptors Target Protein Species: Human Protein Tag: FLAG-tag at N-terminus Host Cell Type: HEK293T Assay Types: Calcium flux assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: GPR68; ARRB2 Target Family: Proton-Sensing Receptors Target Protein Species: Human Protein Tag: FLAG-tag at N-terminus Host Cell Type: HEK293T Assay Types: β-Arrestin Assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: GPR65 Target Family: Proton-Sensing Receptors Target Protein Species: Human Protein Tag: FLAG-tag at N-terminus Host Cell Type: HEK293T Assay Types: cAMP assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: GPR65; ARRB2 Target Family: Proton-Sensing Receptors Target Protein Species: Human Protein Tag: FLAG-tag at N-terminus Host Cell Type: HEK293T Assay Types: β-Arrestin Assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: GPR68 Target Family: SPC/LPC/Proton-sensor Family Target Protein Species: Human Host Cell Type: Caco-2; CHO-K1; HEK293
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: GPR65 Target Family: Orphan Family Target Protein Species: Human Host Cell Type: HeLa;CHO-K1;HEK293 Assay Types: Biological assays