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    Family stable cell lines Neuropeptide FF Family Stable Cell Lines; Innovative Tools, Membrane Protein Drug Discovery.

    mProX™ Human NPFFR1 Stable Cell Line

    [CAT#: S01YF-0923-PY134]
    Product Category:
    Membrane Protein Stable Cell Lines
    Subcategory:
    GPCR Cell Lines

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    Host Cell Type:
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    Product Information

    Target Protein
    NPFFR1
    Target Family
    Neuropeptide FF Family
    Target Protein Species
    Human
    Host Cell Type
    HEK293;CHO-K1
    Target Classification
    GPCR Cell Lines
    Target Research Area
    Metabolic Research
    Related Diseases
    Central Precocious Puberty
    Gene ID
    Human: 64106
    UniProt ID
    Human: Q9GZQ6

    Product Properties

    Biosafety Level
    Level 1
    Activity
    Yes
    Quantity
    10⁶ cells per vial
    Applications
    Neuropeptide FF receptor 1 (NPFFR1) is a G-protein coupled receptor that is activated by the neuropeptide FF (NPFF) peptide. This receptor has been implicated in various physiological processes, including pain modulation, stress responses, and the regulation of reproductive functions. Recent studies have shown that NPFFR1 signaling can influence prolactin secretion, suggesting a role in the reproductive axis. Additionally, NPFFR1 has been associated with neuroendocrine functions, making it a potential target for therapeutic interventions in endocrine disorders. The potential therapeutic applications of NPFFR1 modulation offer exciting prospects for future research and drug development.

    Protocols

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    FAQ

    chat Thomas (Verified Customer)

    What is the significance of membrane protein dynamics in relation to NPFFR1? Jan 03 2021

    chat Patrick Liam (Creative Biolabs Scientific Support)

    Membrane protein dynamics play a crucial role in understanding the behavior and function of proteins like NPFFR1. Time-resolved X-ray scattering in solution has emerged as a powerful tool to track these dynamics, especially when combined with molecular dynamics simulations to identify transient intermediate states. Jan 03 2021

    chat Gary (Verified Customer)

    How can nanodiscs aid in the study of NPFFR1? Mar 25 2020

    chat Patrick Liam (Creative Biolabs Scientific Support)

    Nanodiscs provide a nanometer-scale vehicle for the in vivo delivery of various agents, including active protein complexes like NPFFR1. They have found significant utility in studying cellular signaling complexes that assemble on a membrane surface. Mar 25 2020

    Related Products by Target
    • mProX™ Human NPFFR1 Stable Cell Line (CAT#: S01YF-0923-PY134)
    • Magic™ Human FLAG tagged NPFFR1 HEK293T Cell Line, cAMP assay (CAT#: S01YF-1022-KX470)
    • Magic™ Human NPFFR1 CHO-K1 Cell Line, Binding and Functional Assay (CAT#: S01YF-1222-KX287)
    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR CLINICAL PROCEDURES" For licensing inquiries, please contact
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