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  3. mProX™ Human GLP1R Stable Cell Line
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    mProX™ Human GLP1R Stable Cell Line

    [CAT#: S01YF-0923-PY78]
    Product Category:
    Membrane Protein Stable Cell Lines
    Subcategory:
    GPCR Cell Lines

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    Host Cell Type:
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    Product Information

    Target Protein
    GLP1R
    Target Family
    Glucagon Family
    Target Protein Species
    Rat
    Host Cell Type
    Mesangial;CHO-K1;HEK293
    Target Classification
    GPCR Cell Lines
    Target Research Area
    Metabolic Research
    Related Diseases
    Insulinoma;Hyperglycemia
    Gene ID
    Rat: 25051
    UniProt ID
    Rat: P32301

    Product Properties

    Biosafety Level
    Level 1
    Activity
    Yes
    Quantity
    10⁶ cells per vial
    Applications
    GLP1R is a receptor that plays a significant role in glucose metabolism and appetite regulation. Recent studies have shown that GLP1R can attenuate the sympathetic response to high glucose levels via carotid body inhibition. Additionally, GLP1R gene polymorphisms have been associated with obesity and other metabolic parameters in various populations. Furthermore, GLP1R has been shown to inhibit the progression of endometrial carcinoma through the activation of the cAMP/PKA pathway.

    Protocols

    Please visit our protocols page.

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    FAQ

    chat William (Verified Customer)

    How does GLP1R contribute to glucose homeostasis? Jan 12 2022

    chat Patrick Liam (Creative Biolabs Scientific Support)

    GLP1R, the glucagon-like peptide-1 receptor, mediates the effects of GLP-1, an incretin hormone that enhances insulin secretion, inhibits glucagon release, and slows gastric emptying, thereby contributing to glucose homeostasis. Jan 12 2022

    chat Kathleen (Verified Customer)

    How does GLP1R influence appetite and body weight? Nov 15 2022

    chat Patrick Liam (Creative Biolabs Scientific Support)

    Activation of GLP1R in the central nervous system can reduce appetite and food intake, leading to weight loss and improved metabolic health. Nov 15 2022

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    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR CLINICAL PROCEDURES" For licensing inquiries, please contact
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