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  • Human GLP1R Membrane Protein In Vitro Transcription (IVT) Plasmid

    [CAT#: S01YF-1124-KX1089]
    Product Category:
    Membrane Protein Tools
    Subcategory:
    Membrane Protein Plasmids

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    Certificate of Analysis Lookup
    To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
    Lot Number

    Product Information

    Product Overview
    This product is a made-to-order plasmid encoding human GLP1R for In Vitro Transcription.
    Target Protein
    GLP1R
    Target Protein Species
    Human
    Target Classification
    GPCR
    Target Research Area
    Cancer Research; Diabetes Research; Digestive and Renal Research
    Related Diseases
    Insulinoma; Hyperglycemia
    Target Family
    Glucagon
    Vector
    pIVT
    Vector Type
    In Vitro Transcription (IVT) Vector
    Note
    Resistance
    KanR
    Growth Temperature
    37°C
    Relevant Promoters
    T7
    Mutation
    Based on specific requirements
    Expressed Tags
    Based on specific requirements (Flag, StrepII, His, etc.)

    Product Properties

    Applications
    In Vitro Transcription
    Shipping
    Blue Ice
    Storage
    Aliquot and store at -20°C for long term.

    Target

    Full Name
    Glucagon like peptide 1 receptor
    Introduction
    This gene encodes a 7-transmembrane protein that functions as a receptor for glucagon-like peptide 1 (GLP-1) hormone, which stimulates glucose-induced insulin secretion. This receptor, which functions at the cell surface, becomes internalized in response to GLP-1 and GLP-1 analogs, and it plays an important role in the signaling cascades leading to insulin secretion. It also displays neuroprotective effects in animal models. Polymorphisms in this gene are associated with diabetes. The protein is an important drug target for the treatment of type 2 diabetes and stroke. Alternative splicing of this gene results in multiple transcript variants.
    Alternative Names
    GLP-1; GLP-1R; GLP-1-R;glucagon-like peptide 1 receptor;GLP-1 receptor;GLP1 receptor;seven transmembrane helix receptor;GLP1R
    Gene ID
    UniProt ID

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