GLP1R
This gene encodes a 7-transmembrane protein that serves as a receptor for the hormone glucagon-like peptide-1 (GLP-1), which promotes the release of insulin in response to glucose. This cell surface receptor, which is internalized in response to GLP-1 and GLP-1 analogs, is crucial in the signaling pathways that result in insulin production. In animal models, it also exhibits neuroprotective properties. The protein is an important drug target for the treatment of type 2 diabetes and stroke.
| Full Name | Glucagon like peptide 1 receptor |
| Gene ID | Human: 2740 Mouse: 14652 Rat: 25051 Monkey: 719548 |
| UniProt ID | Human: P43220 Mouse: O35659 Rat: P32301 Monkey: A0A2K6M2Q7 |
| Alternative Names | GLP-1; GLP-1R; GLP-1-R; GLP-1 receptor; GLP1 receptor; seven transmembrane helix receptor; GLP1R; Glucagon like peptide 1 receptor |
Product List
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mProX™ Human GLP1R Stable Cell Line
[CAT#: S01YF-0923-PY78]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: GLP1R Target Family: Glucagon Family Target Protein Species: Rat Host Cell Type: Mesangial;CHO-K1;HEK293
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