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    mProX™ Human CCR7 Stable Cell Line

    [CAT#: S01YF-0923-PY40]
    Product Category:
    Membrane Protein Stable Cell Lines
    Subcategory:
    GPCR Cell Lines

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    Product Information

    Target Protein
    CCR7
    Target Family
    Chemokine Family
    Target Protein Species
    Human
    Host Cell Type
    MCF-7;MDA-MB-231;CHO-K1;HEK293
    Target Classification
    GPCR Cell Lines
    Target Research Area
    Immunology Research
    Related Diseases
    Chronic Graft Versus Host Disease;Pars Planitis
    Gene ID
    Human: 1236
    UniProt ID
    Human: P32248

    Product Properties

    Biosafety Level
    Level 1
    Activity
    Yes
    Quantity
    10⁶ cells per vial
    Applications
    CCR7, or C-C chemokine receptor type 7, is a protein that has been a significant focus in the scientific domain. This receptor plays a crucial role in the migration of dendritic cells and T lymphocytes to the lymph nodes, thereby orchestrating adaptive immune responses. One of the notable findings related to CCR7 is its involvement in the migration, invasion, and survival of leukemic cells, making it a potential therapeutic target in T-cell prolymphocytic leukemia. Furthermore, the CCR7 signaling pathway has been identified as essential in dendritic cell migration, with implications for inflammatory diseases. Another study highlighted the role of the CCL21/CCR7 chemokine axis in breast cancer progression, emphasizing its potential as a therapeutic target. Additionally, the CCR7 network's targeting has been proposed to regulate dendritic cell migration and address inflammatory diseases. Given these findings, CCR7 emerges as a pivotal receptor in understanding various physiological and pathological processes, from immune regulation to cancer progression

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    Customer Reviews

    There are currently no Customer reviews or questions for mProX™ Human CCR7 Stable Cell Line (S01YF-0923-PY40). Click the button above to contact us or submit your feedback about this product.

    FAQ

    chat Shirley (Verified Customer)

    Is CCR7 only associated with lymph node metastasis in cancer? May 13 2021

    chat Patrick Liam (Creative Biolabs Scientific Support)

    While CCR7 is associated with lymph node metastasis, it also plays a crucial role in the migration of T cells and dendritic cells to lymph nodes. May 13 2021

    chat Joseph (Verified Customer)

    Can CCR7 be considered a sole marker for cancer prognosis? Aug 16 2022

    chat Patrick Liam (Creative Biolabs Scientific Support)

    No, while CCR7 expression can be associated with cancer progression, its prognostic value should be considered alongside other factors. Aug 16 2022

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    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR CLINICAL PROCEDURES" For licensing inquiries, please contact
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