CCR7
This gene encodes a protein that belongs to the family of G protein-coupled receptors. This receptor was shown to be an Epstein-Barr virus (EBV)-induced gene, and it is believed to be a mediator of EBV effects on B cells. This receptor induces B and T cell activation and is expressed in a variety of lymphoid organs. It has been demonstrated to promote dendritic cell maturation and regulate memory T cell migration to inflammatory regions. According to reports, this receptor prefers the chemokine (C-C motif) ligand 19 (CCL19/ECL). This receptor's signals may also have a role in the activation and polarization of T cells as well as the pathophysiology of chronic inflammation. They also regulate T cell homeostasis in lymph nodes.
| Full Name | C-C motif chemokine receptor 7 |
| Gene ID | Human: 1236 Mouse: 12775 Rat: 287673 Monkey: 102137559 |
| UniProt ID | Human: P32248 Mouse: P47774 Rat: A0A8I6A7I0 Monkey: A0A2K6TXY2 |
| Alternative Names | BLR2; EBI1; CCR-7; CD197; CDw197; CMKBR7; CC-CKR-7; C-C chemokine receptor type 7; Bukitt's lymphoma receptor 2; CC chemokine receptor 7; EBV-induced G protein-coupled receptor 1; Epstein-Barr virus induced gene 1; Epstein-Barr virus-induced G-protein coupled receptor 1; MIP-3 beta receptor; chemokine (C-C motif) receptor 7; lymphocyte-specific G protein-coupled peptide receptor; CCR7; C-C motif chemokine receptor 7 |
Product List
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Magic™ Human CCR7 CHO-K1 Cell Line with Aequorin Reporter, Calcium flux assay
[CAT#: S01YF-1222-KX346]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CCR7 Target Family: Chemokine Receptor Target Protein Species: Human Host Cell Type: CHO-K1 Assay Types: Calcium flux assay
Magic™ Human CCR7 CHO-K1 Cell Line, Binding and Functional Assay
[CAT#: S01YF-1222-KX347]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CCR7 Target Family: Chemokine Receptor Target Protein Species: Human Host Cell Type: CHO-K1 Assay Types: Binding and Functional Assay
Magic™ Human CCR7 U2OS Cell Line with BLA (Beta-Lactamase) Reporter, Reporter Assay
[CAT#: S01YF-1222-KX41]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CCR7 Target Family: Chemokine Receptor Target Protein Species: Human Host Cell Type: U2OS Assay Types: Reporter Assay
Magic™ Human FLAG tagged CCR7 HEK293T Cell Line, Calcium flux assay
[CAT#: S01YF-1022-KX254]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CCR7 Target Family: Chemokine Target Protein Species: Human Protein Tag: FLAG-tag at N-terminus Host Cell Type: HEK293T Assay Types: Calcium flux assay
Magic™ Human FLAG tagged CCR7 HEK293T Gαqi5 Cell Line, Calcium flux assay
[CAT#: S01YF-1022-KX255]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CCR7 Target Family: Chemokine Target Protein Species: Human Protein Tag: FLAG-tag at N-terminus Host Cell Type: HEK293T Gαqi5 Assay Types: Calcium flux assay
mProX™ Human CCR7 Stable Cell Line
[CAT#: S01YF-0923-PY40]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CCR7 Target Family: Chemokine Family Target Protein Species: Human Host Cell Type: MCF-7;MDA-MB-231;CHO-K1;HEK293
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