mProX™ Human CCR2 Stable Cell Line

[CAT#: S01YF-0923-PY35]

Product Category:: Membrane Protein Stable Cell Lines

Subcategory:: GPCR Cell Lines

Certificate of Analysis Lookup
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number

Bulk Quote

Based on this stable cell line, we also provide cell-based in vitro assays to evaluate the effects of your compounds or antibodies.

Sub Cat	Product Name	Target Protein Species	Host Cell Type	Assay Types
S01YF-1122-KX297	Magic™ Rhesus monkey CCR2 in Vitro Calcium Flux Assay	Rhesus monkey	CHO-K1-Gα16	Calcium Flux Assay
S01YF-1122-KX298	Magic™ Rhesus monkey CCR2 in Vitro Radioligand Binding Assay	Rhesus monkey	CHO-K1	Radioligand Binding Assay
S01YF-1122-KX299	Magic™ Rat CCR2 in Vitro Calcium Flux Assay	Rat	CHO-K1-Gα16	Calcium Flux Assay
S01YF-1122-KX300	Magic™ Rat CCR2 in Vitro cAMP Assay	Rat	CHO-K1	cAMP Assay
S01YF-1122-KX301	Magic™ Rat CCR2 in Vitro Radioligand Binding Assay	Rat	CHO-K1	Radioligand Binding Assay

Product Information

Target Protein

CCR2

Target Family

Chemokine Family

Target Protein Species

Human

Host Cell Type

PC3;C4-2B;CHO-K1;HEK293

Target Classification

GPCR Cell Lines

Target Research Area

Immunology Research

Related Diseases

Human Immunodeficiency Virus Type 1;Acquired Immunodeficiency Syndrome

Gene ID

Human: 729230

UniProt ID

Human: P41597

Product Properties

Biosafety Level

Level 1

Activity

Yes

Quantity

10⁶ cells per vial

Applications

CCR2, or C-C chemokine receptor type 2, is another protein that has been at the forefront of scientific investigations. This receptor is primarily known for its role in mediating the migration of monocytes, which play a crucial role in immune responses. Recent research has highlighted the significance of the CCL2/CCR2 axis in various aspects of cancer pathogenesis. For instance, the CCL2-CCR2 signaling pathway has been identified as a major player in tumor progression, especially in terms of increasing tumor cell proliferation, invasiveness, and shaping the tumor microenvironment. This is achieved through mechanisms such as increased angiogenesis and the recruitment of immunosuppressive cells. Moreover, the CCL2-CCR2 axis has been implicated in immune evasion mechanisms in esophageal carcinogenesis, further emphasizing its potential as a therapeutic target. In essence, the application of CCR2 in scientific research provides valuable insights into the intricate interactions between tumors and the immune system, offering potential avenues for targeted cancer therapies.

Protocols

Please visit our protocols page.

Customer Reviews

There are currently no Customer reviews or questions for mProX™ Human CCR2 Stable Cell Line (S01YF-0923-PY35). Click the button above to contact us or submit your feedback about this product.

FAQ

chat John (Verified Customer)

What is the significance of CCR2 in stabilized cell line research? Mar 22 2023

chat Patrick Liam (Creative Biolabs Scientific Support)

CCR2 is a chemokine receptor that plays a crucial role in various biological processes. In stabilized cell line research, understanding the expression and function of CCR2 can provide insights into cell migration, inflammation, and other related processes. Mar 22 2023

chat Thomas (Verified Customer)

Are there any concerns regarding the genomic integrity of CCR2 in stabilized cell lines? Mar 08 2023

chat Patrick Liam (Creative Biolabs Scientific Support)

Yes, it's essential to ensure the genomic integrity of any gene, including CCR2, when working with stabilized cell lines. Any alterations can affect the cell's behavior and the reliability of research outcomes. Mar 08 2023

Related Products by Target

Online Inquiry

Thank you for your interest in mProX™ Human CCR2 Stable Cell Line. Please provide us with your contact information and your local representative will contact you with a customized quote. Where appropriate, they can also assist you with a(n):

Estimated delivery time for your area;
Product sample or exclusive offer;
In-lab demonstration;

Creative Biolabs does not share your email address with third parties. Creative Biolabs will use your email address to confirm your identity and send you transaction-related emails, promotional and customer service emails in accordance with our privacy policy. You can change your email preferences at any time.