Human S1PR1 Membrane Protein Lentivirus
[CAT#: S01YF-1124-KX91]
- Product Category:
- Membrane Protein Tools
- Subcategory:
- Membrane Protein Lentivirus
Certificate of Analysis Lookup
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Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
Product Information
Product Overview
This product is a made-to-order lentivirus expressed human S1PR1.
Target Protein
S1PR1
Target Classificationp
GPCR
Target Family
Lysophospholipid
Target Protein Species
Human
Protein Tag
Based on specific requirements (Flag, StrepII, His, etc.)
Buffer
HBSS
Titer
≧1.00E+8 TU/mL
Transfer Plasmid Backbone
pCDH or specific requirements
Size
100 uL*10 vials, 1 mL
Fluorescent Markers
EGFP, mCherry etc.
Selection Markers
Puromycin, Hygromycin, Neomycin, Blasticidin etc.
Target Research Area
Autoimmune Research; Inflammation Research; Cardiovascular Research
Related Diseases
Autoimmune Encephalitis; Herpes Zoster Oticus
Quality Control
Titer Determination Method
RT-qPCR
Sterility Testing
Negative
Mycoplasma Testing
Negative
Transfection Efficiency
Positive (if EGFP is included in the transfer plasmid)
Endotoxin Level
Based on specific requirements
Product Properties
Application
Stable cell line generation; Protein expression; Biochemical assays
Safety Notes
Since the HIV genes are expressed from packaging plasmids devoid of the packing signal, none of the HIV genes will be expressed in the transduced cells. The pseudotyped lentiviruses need to be used in a Biosafety Level 2 facility even if they are replication-incompetent.
Shipping
Dry ice
Storage
Store at -80°C and avoid repeated freeze-thaw cycles.
Target
Full Name
Sphingosine-1-phosphate receptor 1
Introduction
The protein encoded by this gene is structurally similar to G protein-coupled receptors and is highly expressed in endothelial cells. It binds the ligand sphingosine-1-phosphate with high affinity and high specificity, and suggested to be involved in the processes that regulate the differentiation of endothelial cells. Activation of this receptor induces cell-cell adhesion. Alternative splicing results in multiple transcript variants.
Alternative Names
EDG1; S1P1; CD363; ECGF1; EDG-1; CHEDG1; D1S3362;sphingosine 1-phosphate receptor 1;S1P receptor 1;S1P receptor Edg-1;endothelial differentiation G-protein coupled receptor 1;endothelial differentiation, sphingolipid G-protein-coupled receptor, 1;sphingosine 1-phosphate receptor EDG1;sphingosine 1-phosphate receptor Edg-1;S1PR1
Gene ID
UniProt ID
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