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S1PR1

This gene encodes a protein that is highly expressed in endothelial cells and shares structural similarities with G protein-coupled receptors. It binds the ligand sphingosine-1-phosphate with high affinity and high specificity, and believed to be involved in the mechanisms that regulate the development of endothelial cells. Cell-cell adhesion is brought on by this receptor's activation. PDGFR-beta signaling pathway and S1P1 pathway are two of its related pathways. Gene Ontology (GO) annotations connected to this gene include G protein-coupled receptor activity and sphingosine-1-phosphate receptor activity.

Full Name Sphingosine-1-phosphate receptor 1
Gene ID Human: 1901
Mouse: 13609
Rat: 29733
Monkey: 716813
UniProt ID Human: P21453
Mouse: O08530
Rat: P48303
Monkey: H9EUW9
Alternative Names EDG1; S1P1; CD363; ECGF1; EDG-1; CHEDG1; D1S3362; sphingosine 1-phosphate receptor 1; S1P receptor 1; S1P receptor Edg-1; endothelial differentiation G-protein coupled receptor 1; endothelial differentiation, sphingolipid G-protein-coupled receptor, 1; sphingosine 1-phosphate receptor EDG1; sphingosine 1-phosphate receptor Edg-1; S1PR1; Sphingosine-1-phosphate receptor 1

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Product Category:
Membrane Protein Stable Cell Lines
Target Protein: S1PR1 Target Family: Lysophospholipid Family Target Protein Species: Human Host Cell Type: Huh7;SK-Hep1;CHO-K1;HEK293
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