S1PR1
This gene encodes a protein that is highly expressed in endothelial cells and shares structural similarities with G protein-coupled receptors. It binds the ligand sphingosine-1-phosphate with high affinity and high specificity, and believed to be involved in the mechanisms that regulate the development of endothelial cells. Cell-cell adhesion is brought on by this receptor's activation. PDGFR-beta signaling pathway and S1P1 pathway are two of its related pathways. Gene Ontology (GO) annotations connected to this gene include G protein-coupled receptor activity and sphingosine-1-phosphate receptor activity.
| Full Name | Sphingosine-1-phosphate receptor 1 |
| Gene ID | Human: 1901 Mouse: 13609 Rat: 29733 Monkey: 716813 |
| UniProt ID | Human: P21453 Mouse: O08530 Rat: P48303 Monkey: H9EUW9 |
| Alternative Names | EDG1; S1P1; CD363; ECGF1; EDG-1; CHEDG1; D1S3362; sphingosine 1-phosphate receptor 1; S1P receptor 1; S1P receptor Edg-1; endothelial differentiation G-protein coupled receptor 1; endothelial differentiation, sphingolipid G-protein-coupled receptor, 1; sphingosine 1-phosphate receptor EDG1; sphingosine 1-phosphate receptor Edg-1; S1PR1; Sphingosine-1-phosphate receptor 1 |
Product List
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Magic™ Human FLAG tagged S1PR1 CHO-K1 Cell Line, cAMP assay
[CAT#: S01YF-1022-KX411]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: S1PR1 Target Family: Lysophospholipid Target Protein Species: Human Protein Tag: FLAG-tag at N-terminus Host Cell Type: CHO-K1 Assay Types: cAMP assay
Magic™ Human FLAG tagged S1PR1 CHO-K1 Gαqi5 Cell Line, Calcium flux assay
[CAT#: S01YF-1022-KX412]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: S1PR1 Target Family: Lysophospholipid Target Protein Species: Human Protein Tag: FLAG-tag at N-terminus Host Cell Type: CHO-K1 Gαqi5 Assay Types: Calcium flux assay
Magic™ Human S1PR1 (NM_001400) Chem-1 Membrane Preparation
[CAT#: S01YF-0722-KX1029]
- Product Category:
- Membranes
- Target Protein: S1P1/EDG1 Target Family: Lysophospholipid Target Protein Species: Human Host Cell Type: Chem-1 Application: GTPγS Assay; Ligand Binding Assay
Magic™ Human S1PR1 (NM_001400) CHO-K1 Gαqi5 Membrane Preparation
[CAT#: S01YF-0722-KX710]
- Product Category:
- Membranes
- Target Protein: S1P1 Target Family: Lysophospholipid Target Protein Species: Human Protein Tag: FLAG-tag at N-terminus Host Cell Type: CHO-K1 Gαqi5 Application: GTPγS Assay; Ligand Binding Assay
Magic™ Human S1PR1 CHO-K1 Cell Line, β-arrestin assay
[CAT#: S01YF-0822-KX323]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: S1PR1 Target Family: Lysophospholipid (S1P) Receptors Target Protein Species: Human Protein Tag: Enzyme tag Host Cell Type: CHO-K1 Assay Types: β-arrestin assay
Magic™ Human S1PR1 (NM_001400) CHO-K1 Membrane Preparation
[CAT#: S01YF-0722-KX709]
- Product Category:
- Membranes
- Target Protein: S1P1 Target Family: Lysophospholipid Target Protein Species: Human Protein Tag: FLAG-tag at N-terminus Host Cell Type: CHO-K1 Application: GTPγS Assay; Ligand Binding Assay
Magic™ Human S1PR1 U2OS Cell Line with BLA (Beta-Lactamase) Reporter, Reporter Assay
[CAT#: S01YF-1222-KX51]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: S1PR1 Target Family: Lysophospholipid Receptor Target Protein Species: Human Host Cell Type: U2OS Assay Types: Reporter Assay
Magic™ Human S1PR1 Cell Line with 14-3-3ε Reporter, LinkLight Assay
[CAT#: S01YF-0323-KX146]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: S1PR1 Target Family: Lysophospholipid Family Target Protein Species: Human Protein Tag: TEV protease Assay Types: 14-3-3 assay
Magic™ Human S1PR1 Chem-4 Cell Line, Calcium flux assay
[CAT#: S01YF-0822-KX856]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: S1PR1 Target Family: Lysophospholipid Receptors Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: Chem-4 Assay Types: Calcium flux assay
Magic™ Human S1PR1 CHO-K1 Cell Line, cAMP assay
[CAT#: S01YF-0822-KX325]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: S1PR1 Target Family: Lysophospholipid (S1P) Receptors Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: CHO-K1 Assay Types: cAMP assay
Magic™ Human S1PR1 HEK293 Cell Line, Internalization assay
[CAT#: S01YF-0822-KX324]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: S1PR1 Target Family: Lysophospholipid (S1P) Receptors Target Protein Species: Human Protein Tag: Enzyme tag Host Cell Type: HEK293 Assay Types: Internalization assay
Magic™ Human S1PR1 HepG2 Cell Line, Internalization assay
[CAT#: S01YF-0822-KX58]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: S1PR1 Target Family: Lysophospholipid (S1P) receptors Target Protein Species: Human Protein Tag: tGFP tag Host Cell Type: HepG2 Assay Types: Internalization Assay
Magic™ Human S1PR1 U2OS Cell Line with pLuc Reporter, LinkLight Assay
[CAT#: S01YF-0323-KX61]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: S1PR1 Target Family: Lysophospholipid Family Target Protein Species: Human Protein Tag: TEV protease Host Cell Type: U2OS Assay Types: β-arrestin assay
Magic™ Mouse S1pr1 CHO-K1 Cell Line, β-arrestin assay
[CAT#: S01YF-0822-KX638]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: S1pr1 Target Family: Lysophospholipid (S1P) Receptors Target Protein Species: Mouse Protein Tag: Enzyme tag Host Cell Type: CHO-K1 Assay Types: β-arrestin assay
Magic™ mPro Human S1PR1 Cell Line
[CAT#: S01YF-1122-KX20]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: S1PR1 Target Family: Lysophospholipid Receptors Target Protein Species: Human
Magic™ Rat S1PR1 Calcium Flux Assay
[CAT#: S01YF-1122-KX576]
- Product Category:
- Membrane Protein Drug Discovery In Vitro Assays
- Target Protein: S1PR1 Target Family: Lysophospholipid Receptor Target Protein Species: Rat Host Cell Type: CHO-K1-Gqi5 Assay Types: Calcium Flux Assay
Magic™ Rat S1PR1 cAMP Assay
[CAT#: S01YF-1122-KX577]
- Product Category:
- Membrane Protein Drug Discovery In Vitro Assays
- Target Protein: S1PR1 Target Family: Lysophospholipid Receptor Target Protein Species: Rat Host Cell Type: CHO-K1 Assay Types: cAMP Assay
mProX™ Human S1PR1 Stable Cell Line
[CAT#: S01YF-0923-PY102]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: S1PR1 Target Family: Lysophospholipid Family Target Protein Species: Human Host Cell Type: Huh7;SK-Hep1;CHO-K1;HEK293 Assay Types: Biological assays
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