Human S1PR1 Membrane Protein In Vitro Transcription (IVT) mRNA
[CAT#: S01YF-1124-KX206]
- Product Category:
- Membrane Protein Tools
- Subcategory:
- Membrane Protein mRNA
Certificate of Analysis Lookup
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Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
Product Information
Product Overview
This product is a made-to-order IVT mRNA encoding human S1PR1.
Target Protein
S1PR1
Target Protein Species
Human
Target Classificationp
GPCR
Target Research Area
Autoimmune Research; Inflammation Research; Cardiovascular Research
Related Diseases
Autoimmune Encephalitis; Herpes Zoster Oticus
Target Family
Lysophospholipid
RNA Type
IVT mRNA
Nucleoside Modification Method
m1Ψ; m5C or specific requirements
Cap
Cap 0; Cap 1 or specific requirements
PolyA Tail (nt)
30 nt; 80 nt; 120 nt or specific requirements
5' UTR
Human globin alpha; 5' UTR seq can be modified according to the specific requirements
Promoter
T7
Tag
Based on specific requirements
Fluorescent Markers
Based on specific requirements
Formation
In Vitro Transcription (IVT) mRNA
Quality Control
OD260/280 (~1.90-2.50)
PASS
Agarose Gel Mobility
PASS
Sequence and Enzyme Digestion
PASS
Product Properties
Application
Drug discovery research and pre-clinical studies
Shipping
Dry Ice
Storage
Aliquot and store at -20°C for long term.
Target
Full Name
Sphingosine-1-phosphate receptor 1
Introduction
The protein encoded by this gene is structurally similar to G protein-coupled receptors and is highly expressed in endothelial cells. It binds the ligand sphingosine-1-phosphate with high affinity and high specificity, and suggested to be involved in the processes that regulate the differentiation of endothelial cells. Activation of this receptor induces cell-cell adhesion. Alternative splicing results in multiple transcript variants.
Alternative Names
EDG1; S1P1; CD363; ECGF1; EDG-1; CHEDG1; D1S3362;sphingosine 1-phosphate receptor 1;S1P receptor 1;S1P receptor Edg-1;endothelial differentiation G-protein coupled receptor 1;endothelial differentiation, sphingolipid G-protein-coupled receptor, 1;sphingosine 1-phosphate receptor EDG1;sphingosine 1-phosphate receptor Edg-1;S1PR1
Gene ID
UniProt ID
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