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  • Human KDR Membrane Protein Lentivirus

    [CAT#: S01YF-1124-KX72]
    Product Category:
    Membrane Protein Tools
    Subcategory:
    Membrane Protein Lentivirus

    Datasheet MSDS Request COA

    Certificate of Analysis Lookup
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    Lot Number

    Product Information

    Product Overview
    This product is a made-to-order lentivirus expressed human KDR.
    Target Protein
    KDR
    Target Classificationp
    Kinases/Enzyme
    Target Family
    Kinases/Enzyme
    Target Protein Species
    Human
    Protein Tag
    Based on specific requirements (Flag, StrepII, His, etc.)
    Buffer
    HBSS
    Titer
    ≧1.00E+8 TU/mL
    Transfer Plasmid Backbone
    pCDH or specific requirements
    Size
    100 uL*10 vials, 1 mL
    Fluorescent Markers
    EGFP, mCherry etc.
    Selection Markers
    Puromycin, Hygromycin, Neomycin, Blasticidin etc.
    Target Research Area
    Cancer Research
    Related Diseases
    Hemangioma

    Quality Control

    Titer Determination Method
    RT-qPCR
    Sterility Testing
    Negative
    Mycoplasma Testing
    Negative
    Transfection Efficiency
    Positive (if EGFP is included in the transfer plasmid)
    Endotoxin Level
    Based on specific requirements

    Product Properties

    Application
    Stable cell line generation; Protein expression; Biochemical assays
    Safety Notes
    Since the HIV genes are expressed from packaging plasmids devoid of the packing signal, none of the HIV genes will be expressed in the transduced cells. The pseudotyped lentiviruses need to be used in a Biosafety Level 2 facility even if they are replication-incompetent.
    Shipping
    Dry ice
    Storage
    Store at -80°C and avoid repeated freeze-thaw cycles.

    Target

    Full Name
    Kinase insert domain receptor
    Introduction
    Vascular endothelial growth factor (VEGF) is a major growth factor for endothelial cells. This gene encodes one of the two receptors of the VEGF. This receptor, known as kinase insert domain receptor, is a type III receptor tyrosine kinase. It functions as the main mediator of VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis and sprouting. The signalling and trafficking of this receptor are regulated by multiple factors, including Rab GTPase, P2Y purine nucleotide receptor, integrin alphaVbeta3, T-cell protein tyrosine phosphatase, etc.. Mutations of this gene are implicated in infantile capillary hemangiomas.
    Alternative Names
    KDR; FLK1; CD309; VEGFR; VEGFR2; vascular endothelial growth factor receptor 2; fetal liver kinase-1; kinase insert domain receptor (a type III receptor tyrosine kinase); protein-tyrosine kinase receptor Flk-1; soluble VEGFR2; tyrosine kinase growth factor receptor; Kinase insert domain receptor
    Gene ID
    UniProt ID

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    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR CLINICAL PROCEDURES" For licensing inquiries, please contact
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