KDR
Vascular endothelial growth factor (VEGF) is a major growth factor for endothelial cells. This gene encodes one of the two receptors of the VEGF. This receptor, known as kinase insert domain receptor, is a type III receptor tyrosine kinase. It functions as the main mediator of VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis and sprouting. The signalling and trafficking of this receptor are regulated by multiple factors, including Rab GTPase, P2Y purine nucleotide receptor, integrin alphaVbeta3, T-cell protein tyrosine phosphatase, etc.. Mutations of this gene are implicated in infantile capillary hemangiomas.
| Full Name | kinase insert domain receptor |
| Gene ID | Human: 3791 Mouse: 16542 Rat: 25589 Monkey: 698293 |
| UniProt ID | Human: P35968 Mouse: P35918 Rat: O08775 |
| Alternative Names | FLK1; CD309; VEGFR; VEGFR2;vascular endothelial growth factor receptor 2;fetal liver kinase-1;kinase insert domain receptor (a type III receptor tyrosine kinase);protein-tyrosine kinase receptor Flk-1;soluble VEGFR2;tyrosine kinase growth factor receptor |
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mProX™ Human KDR Stable Cell Line
[CAT#: S01YF-1123-KX277]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: KDR Target Family: Kinases/Enzyme Drug Discovery Assays and Products Target Protein Species: Human Host Cell Type: CHO-K1; HEK293
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