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  • mProX™ Human KDR Stable Cell Line

    [CAT#: S01YF-1123-KX277]
    Product Category:
    Membrane Protein Stable Cell Lines
    Subcategory:
    Kinase Cell Lines

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    Host Cell Type:
    Membrane Protein Engineering:
    Fluorescent Marker:
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    Product Information

    Target Protein
    KDR
    Target Family
    Kinases/Enzyme Drug Discovery Assays and Products
    Target Protein Species
    Human
    Host Cell Type
    CHO-K1; HEK293
    Target Classification
    Kinase Cell Lines
    Target Research Area
    Cancer Research
    Related Diseases
    Hemangioma, Capillary Infantile and Angioma, Tufted. Among its related pathways are Apoptotic Pathways in Synovial Fibroblasts and GPCR Pathway
    Gene ID
    UniProt ID

    Product Properties

    Biosafety Level
    Level 1
    Activity
    Yes
    Quantity
    10⁶ cells per vial
    Applications
    Another name for the type IV receptor tyrosine kinase, kinase insert domain receptor (KDR), is vascular endothelial growth factor receptor 2 (VEGFR-2). It is encoded by the human gene KDR. KDR is now referred to as CD309, or the cluster of differentiation 309. Fetal Liver Kinase 1 (Flk1) is another name for KDR. The Q472H germline KDR genetic variant has been linked to microvessel density in non-small cell lung cancer (NSCLC) and has been found to impact VEGFR-2 phosphorylation. It has been demonstrated that the kinase insert domain receptor interacts with SHC1, Annexin A5, and SHC2. The customized KDR stable cell line can be used in antibody discovery and development, potential drug candidate screening and signaling pathway researches.

    Protocols

    Please visit our protocols page.

    Customer Reviews

    chat Thomas

    The human KDR cell line is an essential tool for anyone studying drug discovery. Jul 28 2022

    chat Verified Customer

    chat Matthew

    The KDR overexpression cell line is very good to use and is of high quality and safety. Mar 03 2021

    chat Verified Customer

    FAQ

    Any questions about our products? Please visit our frequently asked questions page.

    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR CLINICAL PROCEDURES" For licensing inquiries, please contact
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