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  • Human IGF1R Membrane Protein In Vitro Transcription (IVT) mRNA

    [CAT#: S01YF-1124-KX179]
    Product Category:
    Membrane Protein Tools
    Subcategory:
    Membrane Protein mRNA

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    Certificate of Analysis Lookup
    To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
    Lot Number

    Product Information

    Product Overview
    This product is a made-to-order IVT mRNA encoding human IGF1R.
    Target Protein
    IGF1R
    Target Protein Species
    Human
    Target Classificationp
    Kinases/Enzyme
    Target Research Area
    Metabolic Research
    Related Diseases
    Insulin-Like Growth Factor I; Nk-Cell Enteropathy
    Target Family
    Kinases/Enzyme
    RNA Type
    IVT mRNA
    Nucleoside Modification Method
    m1Ψ; m5C or specific requirements
    Cap
    Cap 0; Cap 1 or specific requirements
    PolyA Tail (nt)
    30 nt; 80 nt; 120 nt or specific requirements
    5' UTR
    Human globin alpha; 5' UTR seq can be modified according to the specific requirements
    Promoter
    T7
    Tag
    Based on specific requirements
    Fluorescent Markers
    Based on specific requirements
    Formation
    In Vitro Transcription (IVT) mRNA

    Quality Control

    OD260/280 (~1.90-2.50)
    PASS
    Agarose Gel Mobility
    PASS
    Sequence and Enzyme Digestion
    PASS

    Product Properties

    Application
    Drug discovery research and pre-clinical studies
    Shipping
    Dry Ice
    Storage
    Aliquot and store at -20°C for long term.

    Target

    Full Name
    Insulin like growth factor 1 receptor
    Introduction
    This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
    Alternative Names
    IGF1R; IGFR; CD221; IGFIR; JTK13; insulin-like growth factor 1 receptor; IGF-I receptor; soluble IGF1R variant 1; soluble IGF1R variant 2; Insulin like growth factor 1 receptor
    Gene ID
    UniProt ID

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    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR CLINICAL PROCEDURES" For licensing inquiries, please contact
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