mProX™ Human IGF1R Stable Cell Line
[CAT#: S01YF-1123-KX262]
- Product Category:
- Membrane Protein Stable Cell Lines
- Subcategory:
- Kinase Cell Lines
Certificate of Analysis Lookup
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
Made to Order Inquiry
InquiryProduct Information
Target Protein
IGF1R
Target Family
Kinases/Enzyme Drug Discovery Assays and Products
Target Protein Species
Human
Host Cell Type
CHO-K1; HEK293
Target Classification
Kinase Cell Lines
Target Research Area
Digestive and Renal Research; Immunology Research; Diabetes Research
Related Diseases
Insulin-Like Growth Factor I and Nk-Cell Enteropathy. Among its related pathways are Apoptotic Pathways in Synovial Fibroblasts and GPCR Pathway
Gene ID
UniProt ID
Product Properties
Biosafety Level
Level 1
Activity
Yes
Quantity
10⁶ cells per vial
Applications
Human cells have a protein called the insulin-like growth factor 1 (IGF-1) receptor on their surface. The hormones insulin-like growth factor 1 (IGF-1) and IGF-2, which are related, both activate this transmembrane receptor. It is a member of the broad class of receptors for tyrosine kinase. The polypeptide protein hormone IGF-1, which shares a chemical structure with insulin, is mediated by this receptor. IGF-1 is crucial for growth and still has anabolic effects in adults, which means it can cause target tissues like skeletal muscle to enlarge. Mice deficient in the IGF-1 receptor exhibit a sharp decline in body mass and die late in development. This demonstrates the receptor's potent growth-promoting ability. The customized IGF1R stable cell line can be used in antibody discovery and development, potential drug candidate screening and signaling pathway researches.
Protocols
Please visit our protocols page.
Customer Reviews
Amy
I am truly impressed with the performance of this IGF1R KO cell line.
Dec 13 2022
Verified Customer
Patricia
I purchased the IGF1R KO cell line from Creative Biolabs. The provided documentation was comprehensive and helped me optimize my assay conditions.
Jul 11 2020
Verified Customer
FAQ
Any questions about our products? Please visit our frequently asked questions page.
