IGF1R
This receptor binds insulin-like growth factor with a high affinity. It has tyrosine kinase activity. The insulin-like growth factor I receptor plays a critical role in transformation events. Cleavage of the precursor generates alpha and beta subunits. It is highly overexpressed in most malignant tissues where it functions as an anti-apoptotic agent by enhancing cell survival. Alternatively spliced transcript variants encoding distinct isoforms have been found for this gene.
| Full Name | insulin like growth factor 1 receptor |
| Gene ID | Human: 3480 Mouse: 16001 Rat: 25718 Monkey: 708227 |
| UniProt ID | Human: P08069 Mouse: Q60751 Rat: P24062 |
| Alternative Names | IGFR; CD221; IGFIR; JTK13;insulin-like growth factor 1 receptor;IGF-I receptor |
Product List
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Magic™ Human IGF1R BaF3 Cell Line
[CAT#: S01YF-1222-KX805]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: IGF1R Target Family: Kinases/Enzyme Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: BaF3 Assay Types: Drug screening and biological assays
mProX™ Human IGF1R Stable Cell Line
[CAT#: S01YF-1123-KX262]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: IGF1R Target Family: Kinases/Enzyme Drug Discovery Assays and Products Target Protein Species: Human Host Cell Type: CHO-K1; HEK293
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