Human FGFR2 Membrane Protein Yeast Expression Plasmid
[CAT#: S01YF-1124-KX627]
- Product Category:
- Membrane Protein Tools
- Subcategory:
- Membrane Protein Plasmids
Certificate of Analysis Lookup
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Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
Product Information
Product Overview
This product is a made-to-order plasmid encoding human FGFR2 for Protein Expression.
Target Protein
FGFR2
Target Protein Species
Human
Target Classification
Kinases/Enzyme
Target Research Area
Metabolic Research
Related Diseases
Pfeiffer Syndrome; Crouzon Syndrome
Target Family
Kinases/Enzyme
Vector
pYE
Vector Type
Yeast Expression Vector
Note
Resistance
AmpR
Growth Temperature
37°C
Relevant Promoters
GAL4, PGK, ADH1, ADE2
Mutation
Based on specific requirements
Expressed Tags
Based on specific requirements (Flag, StrepII, His, etc.)
Product Properties
Applications
Protein Expression
Shipping
Blue Ice
Storage
Aliquot and store at -20°C for long term.
Target
Full Name
Fibroblast growth factor receptor 2
Introduction
The protein encoded by this gene is a member of the fibroblast growth factor receptor family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein consists of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. This particular family member is a high-affinity receptor for acidic, basic and/or keratinocyte growth factor, depending on the isoform. Mutations in this gene are associated with Crouzon syndrome, Pfeiffer syndrome, Craniosynostosis, Apert syndrome, Jackson-Weiss syndrome, Beare-Stevenson cutis gyrata syndrome, Saethre-Chotzen syndrome, and syndromic craniosynostosis. Multiple alternatively spliced transcript variants encoding different isoforms have been noted for this gene.
Alternative Names
FGFR2; BEK; JWS; BBDS; CEK3; CFD1; ECT1; KGFR; TK14; TK25; BFR-1; CD332; K-SAM; BEK fibroblast growth factor receptor; bacteria-expressed kinase; keratinocyte growth factor receptor; protein tyrosine kinase, receptor like 14; Fibroblast growth factor receptor 2
Gene ID
UniProt ID
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