Human EDNRA Membrane Protein In Vitro Transcription (IVT) mRNA
[CAT#: S01YF-1124-KX156]
- Product Category:
- Membrane Protein Tools
- Subcategory:
- Membrane Protein mRNA
Certificate of Analysis Lookup
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Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
Product Information
Product Overview
This product is a made-to-order IVT mRNA encoding human EDNRA.
Target Protein
EDNRA
Target Protein Species
Human
Target Classificationp
GPCR
Target Research Area
Cardiovascular Research; CNS Research; Pain and Addiction Research
Related Diseases
Mandibulofacial Dysostosis With Alopecia; Migraine With Or Without Aura
Target Family
Endothelin Receptor
RNA Type
IVT mRNA
Nucleoside Modification Method
m1Ψ; m5C or specific requirements
Cap
Cap 0; Cap 1 or specific requirements
PolyA Tail (nt)
30 nt; 80 nt; 120 nt or specific requirements
5' UTR
Human globin alpha; 5' UTR seq can be modified according to the specific requirements
Promoter
T7
Tag
Based on specific requirements
Fluorescent Markers
Based on specific requirements
Formation
In Vitro Transcription (IVT) mRNA
Quality Control
OD260/280 (~1.90-2.50)
PASS
Agarose Gel Mobility
PASS
Sequence and Enzyme Digestion
PASS
Product Properties
Application
Drug discovery research and pre-clinical studies
Shipping
Dry Ice
Storage
Aliquot and store at -20°C for long term.
Target
Full Name
Endothelin receptor type A
Introduction
This gene encodes the receptor for endothelin-1, a peptide that plays a role in potent and long-lasting vasoconstriction. This receptor associates with guanine-nucleotide-binding (G) proteins, and this coupling activates a phosphatidylinositol-calcium second messenger system. Polymorphisms in this gene have been linked to migraine headache resistance. Alternative splicing results in multiple transcript variants.
Alternative Names
ETA; ET-A; ETAR; ETRA; MFDA; ETA-R; hET-AR; endothelin-1 receptor; G protein-coupled receptor; endothelin receptor subtype A; endothelin-1-specific receptor; EDNRA; Endothelin receptor type A
Gene ID
UniProt ID
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