EDNRA
This gene encodes the endothelin-1 receptor, a peptide that contributes to powerful and protracted vasoconstriction. Guanine-nucleotide-binding (G) proteins connect with this receptor, and this coupling activates the phosphatidylinositol-calcium second messenger system. Resistance to migraine headaches has been connected to polymorphisms in this gene. The endothelinA receptor (ETA receptor) is a G-protein-coupled receptor that is a part of the endothelin receptor group, which also includes ETB. They are largely found in the vascular smooth muscle, where they contribute to cell growth and vasoconstriction.
Full Name | Endothelin receptor type A |
Gene ID | Human: 1909 Mouse: 13617 Rat: 24326 Monkey: 704135 |
UniProt ID | Human: P25101 Mouse: Q61614 Rat: P26684 Monkey: A0A2K5TPJ0 |
Alternative Names | ETA; ET-A; ETAR; ETRA; MFDA; ETA-R; hET-AR; endothelin-1 receptor; G protein-coupled receptor; endothelin receptor subtype A; endothelin-1-specific receptor; EDNRA; Endothelin receptor type A |
Product List
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: EDNRA Target Family: Endothelin Family Target Protein Species: Human Host Cell Type: KIM-1;KYN-2;CHO-K1;HEK293