Human CLDN18 Membrane Protein Insect Expression Plasmid
[CAT#: S01YF-1124-KX493]
- Product Category:
- Membrane Protein Tools
- Subcategory:
- Membrane Protein Plasmids
Certificate of Analysis Lookup
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Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
Product Information
Product Overview
This product is a made-to-order plasmid encoding human CLDN18 for Protein Expression.
Target Protein
CLDN18
Target Protein Species
Human
Target Classification
Oncology Cell Lines
Target Research Area
Cancer Research
Related Diseases
Gastroesophageal Adenocarcinoma; Gastroesophageal Junction Adenocarcinoma
Target Family
Others
Vector
pIE
Vector Type
Insect Expression Vector
Note
Resistance
AmpR
Growth Temperature
37°C
Relevant Promoters
Polyhedrin
Mutation
Based on specific requirements
Expressed Tags
Based on specific requirements (Flag, StrepII, His, etc.)
Product Properties
Applications
Protein Expression
Shipping
Blue Ice
Storage
Aliquot and store at -20°C for long term.
Target
Full Name
Claudin 18
Introduction
This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. This gene is upregulated in patients with ulcerative colitis and highly overexpressed in infiltrating ductal adenocarcinomas. PKC/MAPK/AP-1 (protein kinase C/mitogen-activated protein kinase/activator protein-1) dependent pathway regulates the expression of this gene in gastric cells. Alternatively spliced transcript variants encoding different isoforms have been identified.
Alternative Names
CLDN18; SFTA5; SFTPJ; claudin-18; surfactant associated 5; surfactant associated protein J; surfactant, pulmonary associated protein J; Claudin 18
Gene ID
UniProt ID
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