CLDN18
This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. This gene is upregulated in patients with ulcerative colitis and highly overexpressed in infiltrating ductal adenocarcinomas. PKC/MAPK/AP-1 (protein kinase C/mitogen-activated protein kinase/activator protein-1) dependent pathway regulates the expression of this gene in gastric cells. Alternatively spliced transcript variants encoding different isoforms have been identified.
| Full Name | Claudin 18 |
| Gene ID | Human: 51208 Mouse: 56492 Rat: 315953 Monkey: 716628 |
| UniProt ID | Human: P56856 Mouse: P56857 Rat: Q5I0E5 Monkey: F6YQY3 |
| Alternative Names | CLDN18; SFTA5; SFTPJ; claudin-18; surfactant associated 5; surfactant associated protein J; surfactant, pulmonary associated protein J; Claudin 18 |
Product List
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Magic™ Cyno CLDN18 HEK293T Cell Line
[CAT#: S01YF-0123-KX35]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CLDN18 Target Family: Others Target Protein Species: Cyno Protein Tag: Tag-free Host Cell Type: HEK293T Assay Types: Drug screening and biological assays
Magic™ Dog CLDN18 HEK293T Cell Line
[CAT#: S01YF-0123-KX31]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CLDN18 Target Family: Others Target Protein Species: Dog Protein Tag: Tag-free Host Cell Type: HEK293T Assay Types: Drug screening and biological assays
Magic™ Human CD47 & CLDN18 & CD276 MC-38 Cell Line
[CAT#: S01YF-0324-KX95]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CD47 & CLDN18 & CD276 Target Family: Immune Checkpoint Target Protein Species: Human Host Cell Type: MC-38 Assay Types: Functional assay and biological assay
Magic™ Human CD47 & CLDN18 & EGFR MC-38 Cell Line
[CAT#: S01YF-0324-KX97]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CD47 & CLDN18 & EGFR Target Family: Immune Checkpoint Target Protein Species: Human Host Cell Type: MC-38 Assay Types: Functional assay and biological assay
Magic™ Human CD47 & CLDN18 & GPC3 MC-38 Cell Line
[CAT#: S01YF-0324-KX98]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CD47 & CLDN18 & GPC3 Target Family: Immune Checkpoint Target Protein Species: Human Host Cell Type: MC-38 Assay Types: Functional assay and biological assay
Magic™ Human CD47 & CLDN18 & HER3 MC-38 Cell Line
[CAT#: S01YF-0324-KX101]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CD47 & CLDN18 & HER3 Target Family: Immune Checkpoint Target Protein Species: Human Host Cell Type: MC-38 Assay Types: Functional assay and biological assay
Magic™ Human CD47 & CLDN18 & VTCN1 MC-38 Cell Line
[CAT#: S01YF-0324-KX96]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CD47 & CLDN18 & VTCN1 Target Family: Immune Checkpoint Target Protein Species: Human Host Cell Type: MC-38 Assay Types: Functional assay and biological assay
Magic™ Human CD47 & CLDN18 MC-38 Cell Line
[CAT#: S01YF-0324-KX106]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CD47 & CLDN18 Target Family: Immune Checkpoint Target Protein Species: Human Host Cell Type: MC-38 Assay Types: Functional assay and biological assay
Magic™ Human CLDN18.1 CHO-K1 Cell Line
[CAT#: S01YF-0123-KX253]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CLDN18.1 Target Family: Others Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: CHO-K1 Assay Types: Drug screening and biological assays
Magic™ Human CLDN18.1 HEK293T Cell Line
[CAT#: S01YF-0123-KX302]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CLDN18.1 Target Family: Others Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: HEK293T Assay Types: Drug screening and biological assays
Magic™ Human CLDN18.1 HEK293T Cell Line, Flag-Tag
[CAT#: S01YF-0123-KX232]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CLDN18.1 Target Family: Others Target Protein Species: Human Protein Tag: Flag-Tag Host Cell Type: HEK293T Assay Types: Drug screening and biological assays
Magic™ Human CLDN18.2 (A42S, N45Q, Q47E, E56Q) HEK293T Cell Line
[CAT#: S01YF-0123-KX212]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CLDN18.2 (A42S, N45Q, Q47E, E56Q) Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: HEK293T Assay Types: Drug screening and biological assays
Magic™ Human CLDN18.2 Bxpc3 Cell Line
[CAT#: S01YF-0123-KX229]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CLDN18.2 Target Family: Others Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: Bxpc3 Assay Types: Drug screening and biological assays
Magic™ Human CLDN18.2 BxPC3 Cell Line with Luc2 Reporter
[CAT#: S01YF-1222-KX959]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CLDN18.2 Target Family: Others Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: BxPC3 Assay Types: Drug screening and biological assays
Magic™ Human CLDN18.2 CHO-K1 Cell Line
[CAT#: S01YF-0123-KX254]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CLDN18.2 Target Family: Others Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: CHO-K1 Assay Types: Drug screening and biological assays
Magic™ Human CLDN18.2 CT26 Cell Line
[CAT#: S01YF-0123-KX250]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CLDN18.2 Target Family: Others Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: CT26 Assay Types: Drug screening and biological assays
Magic™ Human CLDN18.2 HEK293T Cell Line
[CAT#: S01YF-0123-KX303]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CLDN18.2 Target Family: Others Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: HEK293T Assay Types: Drug screening and biological assays
Magic™ Human CLDN18.2 KATOIII Cell Line
[CAT#: S01YF-0123-KX187]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CLDN18.2 Target Family: Others Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: KATOIII Assay Types: Drug screening and biological assays
Magic™ Human CLDN18.2 MC38 Cell Line
[CAT#: S01YF-0123-KX189]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CLDN18.2 Target Family: Others Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: MC38 Assay Types: Drug screening and biological assays
Magic™ Human CLDN18.2 MFC Cell Line
[CAT#: S01YF-0123-KX171]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CLDN18.2 Target Family: Others Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: MFC Assay Types: Drug screening and biological assays
Magic™ Human CLDN18.2 MIAPaCa2 Cell Line
[CAT#: S01YF-0123-KX160]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CLDN18.2 Target Family: Others Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: MIAPaCa2 Assay Types: Drug screening and biological assays
Magic™ Human CLDN18.2 MKN45 Cell Line
[CAT#: S01YF-0123-KX103]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CLDN18.2 Target Family: Others Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: MKN45 Assay Types: Drug screening and biological assays
Magic™ Human CLDN18.2 NCIN87 Cell Line
[CAT#: S01YF-0123-KX247]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CLDN18.2 Target Family: Others Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: NCIN87 Assay Types: Drug screening and biological assays
Magic™ Human CLDN18.2 NUGC4 Cell Line
[CAT#: S01YF-0123-KX70]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CLDN18.2 Target Family: Others Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: NUGC4 Assay Types: Drug screening and biological assays
Magic™ Mouse CLDN18.2 HEK293T Cell Line
[CAT#: S01YF-0123-KX285]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CLDN18.2 Target Family: Others Target Protein Species: Mouse Protein Tag: Tag-free Host Cell Type: HEK293T Assay Types: Drug screening and biological assays
Magic™ Rat CLDN18.1 HEK293T Cell Line
[CAT#: S01YF-0123-KX148]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CLDN18.1 Target Family: Others Target Protein Species: Rat Protein Tag: Tag-free Host Cell Type: HEK293T Assay Types: Drug screening and biological assays
Magic™ Rat CLDN18.2 HEK293T Cell Line
[CAT#: S01YF-0123-KX147]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CLDN18.2 Target Family: Others Target Protein Species: Rat Protein Tag: Tag-free Host Cell Type: HEK293T Assay Types: Drug screening and biological assays
mProX™ Human CLDN18 Stable Cell Line
[CAT#: S01YF-1023-PY261]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Family: Other Targets Target Protein Species: Human Host Cell Type: HEK293;CHO-K1;BGC-823 Assay Types: Biological assays
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