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  • Human CLDN18 Membrane Protein Yeast Expression Plasmid

    [CAT#: S01YF-1124-KX608]
    Product Category:
    Membrane Protein Tools
    Subcategory:
    Membrane Protein Plasmids

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    Certificate of Analysis Lookup
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    Lot Number

    Product Information

    Product Overview
    This product is a made-to-order plasmid encoding human CLDN18 for Protein Expression.
    Target Protein
    CLDN18
    Target Protein Species
    Human
    Target Classification
    Oncology Cell Lines
    Target Research Area
    Cancer Research
    Related Diseases
    Gastroesophageal Adenocarcinoma; Gastroesophageal Junction Adenocarcinoma
    Target Family
    Others
    Vector
    pYE
    Vector Type
    Yeast Expression Vector
    Note
    Resistance
    AmpR
    Growth Temperature
    37°C
    Relevant Promoters
    GAL4, PGK, ADH1, ADE2
    Mutation
    Based on specific requirements
    Expressed Tags
    Based on specific requirements (Flag, StrepII, His, etc.)

    Product Properties

    Applications
    Protein Expression
    Shipping
    Blue Ice
    Storage
    Aliquot and store at -20°C for long term.

    Target

    Full Name
    Claudin 18
    Introduction
    This gene encodes a member of the claudin family. Claudins are integral membrane proteins and components of tight junction strands. Tight junction strands serve as a physical barrier to prevent solutes and water from passing freely through the paracellular space between epithelial or endothelial cell sheets, and also play critical roles in maintaining cell polarity and signal transductions. This gene is upregulated in patients with ulcerative colitis and highly overexpressed in infiltrating ductal adenocarcinomas. PKC/MAPK/AP-1 (protein kinase C/mitogen-activated protein kinase/activator protein-1) dependent pathway regulates the expression of this gene in gastric cells. Alternatively spliced transcript variants encoding different isoforms have been identified.
    Alternative Names
    CLDN18; SFTA5; SFTPJ; claudin-18; surfactant associated 5; surfactant associated protein J; surfactant, pulmonary associated protein J; Claudin 18
    Gene ID
    UniProt ID

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    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR CLINICAL PROCEDURES" For licensing inquiries, please contact
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