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TPR

This gene encodes a large coiled-coil protein that forms intranuclear filaments attached to the inner surface of nuclear pore complexes (NPCs). The protein directly interacts with several components of the NPC. It is required for the nuclear export of mRNAs and some proteins. Oncogenic fusions of the 5' end of this gene with several different kinase genes occur in some neoplasias.

Full Name Translocated promoter region, nuclear basket protein
Gene ID Human: 7175
Mouse: 108989
Rat: 304862
Monkey: 713910
UniProt ID Human: P12270
Mouse: F6ZDS4
Rat: F1MA98
Monkey: A0A5F7ZP61
Alternative Names nucleoprotein TPR; NPC-associated intranuclear protein; megator; nuclear pore complex-associated protein TPR; translocated promoter region (to activated MET oncogene); translocated promoter region protein; tumor potentiating region

Product List

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Product Category:
Membrane Protein Stable Cell Lines
Target Protein: TPR & MET (D1228A) Target Family: Kinases/Enzyme Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: BaF3 Assay Types: Drug screening and biological assays
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: TPR & MET (D1228E) Target Family: Kinases/Enzyme Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: BaF3 Assay Types: Drug screening and biological assays
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: TPR & MET (D1228G) Target Family: Kinases/Enzyme Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: BaF3 Assay Types: Drug screening and biological assays
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: TPR & MET (D1228H) Target Family: Kinases/Enzyme Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: BaF3 Assay Types: Drug screening and biological assays
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: TPR & MET (D1228N) Target Family: Kinases/Enzyme Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: BaF3 Assay Types: Drug screening and biological assays
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: TPR & MET (D1228Y) Target Family: Kinases/Enzyme Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: BaF3 Assay Types: Drug screening and biological assays
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: TPR & MET (F1200I) Target Family: Kinases/Enzyme Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: BaF3 Assay Types: Drug screening and biological assays
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: TPR & MET (F1200L) Target Family: Kinases/Enzyme Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: BaF3 Assay Types: Drug screening and biological assays
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: TPR & MET (G1163R) Target Family: Kinases/Enzyme Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: BaF3 Assay Types: Drug screening and biological assays
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: TPR & MET (L1195F) Target Family: Kinases/Enzyme Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: BaF3 Assay Types: Drug screening and biological assays
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: TPR & MET (L1195V) Target Family: Kinases/Enzyme Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: BaF3 Assay Types: Drug screening and biological assays
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: TPR & MET (Y1230C) Target Family: Kinases/Enzyme Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: BaF3 Assay Types: Drug screening and biological assays
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: TPR & MET (Y1230D) Target Family: Kinases/Enzyme Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: BaF3 Assay Types: Drug screening and biological assays
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: TPR & MET (Y1230H) Target Family: Kinases/Enzyme Target Protein Species: Human Host Cell Type: BaF3 Assay Types: Functional assay and biological assay
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: TPR & MET (Y1230N) Target Family: Kinases/Enzyme Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: BaF3 Assay Types: Drug screening and biological assays
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: TPR & MET (Y1230S) Target Family: Kinases/Enzyme Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: BaF3 Assay Types: Drug screening and biological assays
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: TPR & MET Target Family: Kinases/Enzyme Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: BaF3 Assay Types: Drug screening and biological assays
mProX™ Human TPR Stable Cell Line [CAT#: S01YF-1023-PY143]

Product Category:
Membrane Protein Stable Cell Lines
Target Family: Kinases/Enzyme Target Protein Species: Human Host Cell Type: HEK293;CHO-K1;A549;HeLa Assay Types: Biological assays
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