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    mProX™ Human TPR Stable Cell Line

    [CAT#: S01YF-1023-PY143]
    Product Category:
    Membrane Protein Stable Cell Lines
    Subcategory:
    Kinase Cell Lines

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    Host Cell Type:
    Membrane Protein Engineering:
    Fluorescent Marker:
    Resistance:
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    Product Information

    Target Family
    Kinases/Enzyme
    Target Protein Species
    Human
    Host Cell Type
    HEK293;CHO-K1;A549;HeLa
    Target Classification
    Kinase Cell Lines
    Target Research Area
    Metabolic Research
    Related Diseases
    Intellectual Developmental Disorder, Autosomal Recessive 79; Camptodactyly-Arthropathy-Coxa Vara-Pericarditis Syndrome
    Gene ID
    Human:7175
    UniProt ID
    Human:P12270

    Product Properties

    Biosafety Level
    Level 1
    Activity
    Yes
    Quantity
    10⁶ cells per vial
    Applications
    The application of TPR (Tongue Pressure Resistance) can be summarized as follows: In a study conducted on nasopharyngeal carcinoma patients with dysphagia, a novel system with multisite flexible sensors was used to measure tongue pressure changes. The study found that tongue pressure significantly decreased in patients with dysphagia, with the most pronounced drop in pressure observed in the posterior tongue region (TPR). The study suggests that attention should be paid to pressure training of the TPR during treatments. Additionally, the study found that the endurance time of the anterior and central tongue regions increased significantly, indicating compensation for bolus transport. Therefore, clinical rehabilitation strategies should focus on increasing endurance time training in patients to improve the effectiveness of the swallowing process.

    Protocols

    Please visit our protocols page.

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    FAQ

    chat Jordan Williams (Verified Customer)

    What is the function of the TPR protein in cells? Mar 25 2021

    chat Patrick Liam (Creative Biolabs Scientific Support)

    TPR plays a crucial role in protecting cells from RNA-mediated replication stress and is involved in mRNA export and gene expression regulation. Mar 25 2021

    chat Cameron Miller (Verified Customer)

    How does TPR affect mRNA and lncRNA export? Jan 24 2020

    chat Patrick Liam (Creative Biolabs Scientific Support)

    TPR is required for the efficient nuclear export of mRNAs and lncRNAs, especially from short and intron-poor genes. Jan 24 2020

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