ROR1
This gene encodes a receptor tyrosine kinase-like orphan receptor that modulates neurite growth in the central nervous system. The encoded protein is a glycosylated type I membrane protein that belongs to the ROR subfamily of cell surface receptors. It is a pseudokinase that lacks catalytic activity and may interact with the non-canonical Wnt signalling pathway. This gene is highly expressed during early embryonic development but expressed at very low levels in adult tissues. Increased expression of this gene is associated with B-cell chronic lymphocytic leukaemia. Alternative splicing results in multiple transcript variants encoding different isoforms.
Full Name | Receptor tyrosine kinase like orphan receptor 1 |
Gene ID | Human: 4919 Mouse: 26563 Rat: 362550 Monkey: 700760 |
UniProt ID | Human: Q01973 Mouse: Q9Z139 Rat: D3ZZ97 Monkey: F6RUP2 |
Alternative Names | ROR1; NTRKR1; dJ537F10.1; inactive tyrosine-protein kinase transmembrane receptor ROR1; neurotrophic tyrosine kinase, receptor-related 1; Receptor tyrosine kinase like orphan receptor 1 |
Product List
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: ROR1 Target Family: Others Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: CHO-K1 Assay Types: Drug screening and biological assays
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: ROR1 Target Family: Others Target Protein Species: Human Host Cell Type: CHO-S Assay Types: Functional assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: ROR1 Target Family: Others Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: CT26 Assay Types: Drug screening and biological assays
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: ROR1 Target Family: Others Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: HEK293T Assay Types: Drug screening and biological assays
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: ROR1 Target Family: Others Target Protein Species: Human Host Cell Type: K562 Assay Types: Functional assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: ROR1 Target Family: Others Target Protein Species: Human Host Cell Type: MC-38 Assay Types: Functional assay and biological assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Family: Other Targets Target Protein Species: Human Host Cell Type: HEK293;CHO-K1;KLE