Human ROR1 Membrane Protein In Vitro Transcription (IVT) mRNA
[CAT#: S01YF-1124-KX205]
- Product Category:
- Membrane Protein Tools
- Subcategory:
- Membrane Protein mRNA
Certificate of Analysis Lookup
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Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
Product Information
Product Overview
This product is a made-to-order IVT mRNA encoding human ROR1.
Target Protein
ROR1
Target Protein Species
Human
Target Classificationp
Others
Target Research Area
Auditory and Otology Research
Related Diseases
Deafness
Target Family
Others
RNA Type
IVT mRNA
Nucleoside Modification Method
m1Ψ; m5C or specific requirements
Cap
Cap 0; Cap 1 or specific requirements
PolyA Tail (nt)
30 nt; 80 nt; 120 nt or specific requirements
5' UTR
Human globin alpha; 5' UTR seq can be modified according to the specific requirements
Promoter
T7
Tag
Based on specific requirements
Fluorescent Markers
Based on specific requirements
Formation
In Vitro Transcription (IVT) mRNA
Quality Control
OD260/280 (~1.90-2.50)
PASS
Agarose Gel Mobility
PASS
Sequence and Enzyme Digestion
PASS
Product Properties
Application
Drug discovery research and pre-clinical studies
Shipping
Dry Ice
Storage
Aliquot and store at -20°C for long term.
Target
Full Name
Receptor tyrosine kinase like orphan receptor 1
Introduction
This gene encodes a receptor tyrosine kinase-like orphan receptor that modulates neurite growth in the central nervous system. The encoded protein is a glycosylated type I membrane protein that belongs to the ROR subfamily of cell surface receptors. It is a pseudokinase that lacks catalytic activity and may interact with the non-canonical Wnt signalling pathway. This gene is highly expressed during early embryonic development but expressed at very low levels in adult tissues. Increased expression of this gene is associated with B-cell chronic lymphocytic leukaemia. Alternative splicing results in multiple transcript variants encoding different isoforms.
Alternative Names
ROR1; NTRKR1; dJ537F10.1; inactive tyrosine-protein kinase transmembrane receptor ROR1; neurotrophic tyrosine kinase, receptor-related 1; Receptor tyrosine kinase like orphan receptor 1
Gene ID
UniProt ID
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