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    mProX™ Human ROR1 Stable Cell Line

    [CAT#: S01YF-1023-PY285]
    Product Category:
    Membrane Protein Stable Cell Lines
    Subcategory:

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    Host Cell Type:
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    Product Information

    Target Family
    Other Targets
    Target Protein Species
    Human
    Host Cell Type
    HEK293;CHO-K1;KLE
    Target Classification
    Other Targets Drug Discovery Assays and Products
    Target Research Area
    CNS Research;Cardisvascular Research
    Related Diseases
    Deafness, Autosomal Recessive 108; Rare Autosomal Recessive Non-Syndromic Sensorineural Deafness Type Dfnb
    Gene ID
    Human:4919
    UniProt ID
    Human:Q01973

    Product Properties

    Biosafety Level
    Level 1
    Activity
    Yes
    Quantity
    10⁶ cells per vial
    Applications
    ROR1, a marker antigen recommended by the European Research Initiative on Chronic Lymphocytic Leukemia (CLL), is used in the assessment of measurable residual disease (MRD) in CLL patients. A new nine-color assay for CLL MRD using ROR1 has been developed, which is comparable to the standardized methods based on flow cytometry and real-time quantitative PCR. ROR1 has also been investigated as a tumor biomarker in breast cancer, showing significant correlations with other biomarkers such as HER3 and playing a role in prognosis and prediction of treatment response. Additionally, ROR1 has been targeted for the treatment of triple negative breast cancer using small molecules. In cholangiocarcinoma, ROR1-AS1, a long non-coding RNA, has been found to promote cell proliferation and invasion. Furthermore, ROR1 has been utilized in the accurate classification of childhood medulloblastoma subgroups, aiding in appropriate treatment and targeted therapies.

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    FAQ

    chat Peyton Jones (Verified Customer)

    How does ROR1 expression affect cancer survival? Jun 10 2020

    chat Patrick Liam (Creative Biolabs Scientific Support)

    ROR1 expression is associated with adverse outcomes in cancer survival, highlighting its potential as a target for cancer therapeutics. Jun 10 2020

    chat Alex Johnson (Verified Customer)

    What is the role of ROR1 in breast cancer? Jun 01 2023

    chat Patrick Liam (Creative Biolabs Scientific Support)

    ROR1 is expressed in human breast cancers and is associated with enhanced tumor-cell growth, indicating its biological and clinical significance. Jun 01 2023

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    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR CLINICAL PROCEDURES" For licensing inquiries, please contact
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