PDGFRA
This gene encodes a receptor for the family of platelet-derived growth factors on the cell surface. These growth factors function as mitogens in mesenchymal stem cells. Whether a functional receptor is a homodimer or a heterodimer, made up of both platelet-derived growth factor receptor alpha and beta polypeptides, depends on the type of growth factor that is coupled to a receptor monomer. According to studies, this gene is involved in the growth of tumors, the healing of wounds, and the formation of new organs. Idiopathic hypereosinophilic syndrome, somatic and familial gastrointestinal stromal tumors, and a number of other malignancies have all been linked to mutations in this gene.
Full Name | Platelet derived growth factor receptor alpha |
Gene ID | Human: 5156 Mouse: 18595 Rat: 25267 Monkey: 697002 |
UniProt ID | Human: P16234 Mouse: P26618 Rat: P20786 Monkey: G7MTB0 |
Alternative Names | PDGFRA; CD140A; PDGFR2; PDGFR-2; platelet-derived growth factor receptor alpha; CD140 antigen-like family member A; CD140a antigen; PDGF-R-alpha; alpha-type platelet-derived growth factor receptor; platelet-derived growth factor receptor 2; platelet-derived growth factor receptor, alpha polypeptide; Platelet derived growth factor receptor alpha |
Product List
- Product Category:
- Membrane Protein Tools
- Target Protein: PDGFRa Target Family: Kinases/Enzyme Vector: pBE Vector Type: Bacterial Expression Vector
- Product Category:
- Membrane Protein Tools
- Target Protein: PDGFRa Target Family: Kinases/Enzyme RNA Type: IVT mRNA Formation: In Vitro Transcription (IVT) mRNA
- Product Category:
- Membrane Protein Tools
- Target Protein: PDGFRa Target Family: Kinases/Enzyme Vector: pIVT Vector Type: In Vitro Transcription (IVT) Vector
- Product Category:
- Membrane Protein Tools
- Target Protein: PDGFRa Target Family: Kinases/Enzyme Vector: pIE Vector Type: Insect Expression Vector
- Product Category:
- Membrane Protein Tools
- Target Protein: PDGFRa Target Family: Kinases/Enzyme Vector: pLV Vector Type: Lentiviral Expression Vector
- Product Category:
- Membrane Protein Tools
- Target Protein: PDGFRa Target Family: Kinases/Enzyme
- Product Category:
- Membrane Protein Tools
- Target Protein: PDGFRa Target Family: Kinases/Enzyme RNA Type: LNP-mRNA Formation: LNP Encapsulation mRNA
- Product Category:
- Membrane Protein Tools
- Target Protein: PDGFRa Target Family: Kinases/Enzyme Vector: pME Vector Type: Mammalian Transient Expression Vector
- Product Category:
- Membrane Protein Tools
- Target Protein: PDGFRa Target Family: Kinases/Enzyme Vector: pRV Vector Type: Retroviral Expression Vector
- Product Category:
- Membrane Protein Tools
- Target Protein: PDGFRa Target Family: Kinases/Enzyme Vector: pYE Vector Type: Yeast Expression Vector
- Product Category:
- Membranes
- Target Protein: PDGFRA Target Family: Kinases/Enzyme Target Protein Species: Human Protein Tag: Based on specific requirements Host Cell Type: Based on specific requirements Application: Binding Assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: PDGFRA Target Family: Kinases/Enzyme Drug Discovery Assays and Products Target Protein Species: Human Host Cell Type: CHO-K1; HEK293