PDGFRA
This gene encodes a receptor for the family of platelet-derived growth factors on the cell surface. These growth factors function as mitogens in mesenchymal stem cells. Whether a functional receptor is a homodimer or a heterodimer, made up of both platelet-derived growth factor receptor alpha and beta polypeptides, depends on the type of growth factor that is coupled to a receptor monomer. According to studies, this gene is involved in the growth of tumors, the healing of wounds, and the formation of new organs. Idiopathic hypereosinophilic syndrome, somatic and familial gastrointestinal stromal tumors, and a number of other malignancies have all been linked to mutations in this gene.
| Full Name | Platelet derived growth factor receptor alpha |
| Gene ID | Human: 5156 Mouse: 18595 Rat: 25267 Monkey: 697002 |
| UniProt ID | Human: P16234 Mouse: P26618 Rat: P20786 Monkey: G7MTB0 |
| Alternative Names | PDGFRA; CD140A; PDGFR2; PDGFR-2; platelet-derived growth factor receptor alpha; CD140 antigen-like family member A; CD140a antigen; PDGF-R-alpha; alpha-type platelet-derived growth factor receptor; platelet-derived growth factor receptor 2; platelet-derived growth factor receptor, alpha polypeptide; Platelet derived growth factor receptor alpha |
Product List
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Magic™ Human PDGFRa & FIP1L1 (D842V) BaF3 Cell Line
[CAT#: S01YF-1222-KX759]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: PDGFRa & FIP1L1 (D842V) Target Family: Kinases/Enzyme Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: BaF3 Assay Types: Drug screening and biological assays
Magic™ Human PDGFRa (D842V) BaF3 Cell Line
[CAT#: S01YF-1222-KX773]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: PDGFRa (D842V) Target Family: Kinases/Enzyme Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: BaF3 Assay Types: Drug screening and biological assays
Magic™ Human PDGFRa (D842V, G652E) BaF3 Cell Line
[CAT#: S01YF-1222-KX537]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: PDGFRa (D842V, G652E) Target Family: Kinases/Enzyme Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: BaF3 Assay Types: Drug screening and biological assays
Magic™ Human PDGFRa (D842V, QGPins) BaF3 Cell Line
[CAT#: S01YF-1222-KX538]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: PDGFRa (D842V, QGPins) Target Family: Kinases/Enzyme Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: BaF3 Assay Types: Drug screening and biological assays
Magic™ Human PDGFRa (D842V, T674I) BaF3 Cell Line
[CAT#: S01YF-1222-KX534]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: PDGFRa (D842V, T674I) Target Family: Kinases/Enzyme Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: BaF3 Assay Types: Drug screening and biological assays
Magic™ Human PDGFRa BaF3 Cell Line
[CAT#: S01YF-1222-KX751]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: PDGFRa Target Family: Kinases/Enzyme Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: BaF3 Assay Types: Drug screening and biological assays
Magic™ Human PDGFRA Cell Membrane Isolation Product
[CAT#: S01YF-1022-KX646]
- Product Category:
- Membranes
- Target Protein: PDGFRA Target Family: Kinases/Enzyme Target Protein Species: Human Protein Tag: Based on specific requirements Host Cell Type: Based on specific requirements Application: Binding Assay
mProX™ Human PDGFRA Stable Cell Line
[CAT#: S01YF-1123-KX138]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: PDGFRA Target Family: Kinases/Enzyme Drug Discovery Assays and Products Target Protein Species: Human Host Cell Type: CHO-K1; HEK293
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