NTRK1
This gene encodes a member of the neurotrophic tyrosine kinase receptor (NTKR) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. The presence of this kinase leads to cell differentiation and may play a role in specifying sensory neuron subtypes. Mutations in this gene have been associated with congenital insensitivity to pain, anhidrosis, self-mutilating behavior, cognitive disability and cancer. Alternate transcriptional splice variants of this gene have been found, but only three have been characterized to date.
Full Name | neurotrophic receptor tyrosine kinase 1 |
Gene ID | Human: 4914 Mouse: 18211 Rat: 59109 Monkey: 719670 |
UniProt ID | Human: P04629 Mouse: Q3UFB7 Rat: P35739 |
Alternative Names | MTC; TRK; TRK1; TRKA; Trk-A; p140-TrkA;high affinity nerve growth factor receptor;Oncogene TRK;TRK1-transforming tyrosine kinase protein;gp140trk;neurotrophic tyrosine kinase, receptor, type 1;tropomyosin-related kinase A;tyrosine kinase receptor A |
Product List
- Product Category:
- Membrane Protein Tools
- Target Protein: NTRK1 Target Family: Kinases/Enzyme Vector: pBE Vector Type: Bacterial Expression Vector
- Product Category:
- Membrane Protein Tools
- Target Protein: NTRK1 Target Family: Kinases/Enzyme RNA Type: IVT mRNA Formation: In Vitro Transcription (IVT) mRNA
- Product Category:
- Membrane Protein Tools
- Target Protein: NTRK1 Target Family: Kinases/Enzyme Vector: pIVT Vector Type: In Vitro Transcription (IVT) Vector
- Product Category:
- Membrane Protein Tools
- Target Protein: NTRK1 Target Family: Kinases/Enzyme Vector: pIE Vector Type: Insect Expression Vector
- Product Category:
- Membrane Protein Tools
- Target Protein: NTRK1 Target Family: Kinases/Enzyme Vector: pLV Vector Type: Lentiviral Expression Vector
- Product Category:
- Membrane Protein Tools
- Target Protein: NTRK1 Target Family: Kinases/Enzyme
- Product Category:
- Membrane Protein Tools
- Target Protein: NTRK1 Target Family: Kinases/Enzyme RNA Type: LNP-mRNA Formation: LNP Encapsulation mRNA
- Product Category:
- Membrane Protein Tools
- Target Protein: NTRK1 Target Family: Kinases/Enzyme Vector: pME Vector Type: Mammalian Transient Expression Vector
- Product Category:
- Membrane Protein Tools
- Target Protein: NTRK1 Target Family: Kinases/Enzyme Vector: pRV Vector Type: Retroviral Expression Vector
- Product Category:
- Membrane Protein Tools
- Target Protein: NTRK1 Target Family: Kinases/Enzyme Vector: pYE Vector Type: Yeast Expression Vector
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: TFG & NTRK1 Target Family: Kinases/Enzyme Target Protein Species: Human Host Cell Type: BaF3 Assay Types: Functional assay and biological assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: TPM3 & NTRK1 (F589L) Target Family: Kinases/Enzyme Target Protein Species: Human Host Cell Type: BaF3 Assay Types: Functional assay and biological assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: TPM3 & NTRK1 (G595R) Target Family: Kinases/Enzyme Target Protein Species: Human Host Cell Type: BaF3 Assay Types: Functional assay and biological assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: TPM3 & NTRK1 (G667C) Target Family: Kinases/Enzyme Target Protein Species: Human Host Cell Type: BaF3 Assay Types: Functional assay and biological assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: TPM3 & NTRK1 (V573M) Target Family: Kinases/Enzyme Target Protein Species: Human Host Cell Type: BaF3 Assay Types: Functional assay and biological assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: TPM3 & NTRK1 Target Family: Kinases/Enzyme Target Protein Species: Human Host Cell Type: BaF3 Assay Types: Functional assay and biological assay
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Family: Kinases/Enzyme Target Protein Species: Human Host Cell Type: HEK293;CHO-K1;PANC-1;MDA-MB-231