NTRK1
This gene encodes a member of the neurotrophic tyrosine kinase receptor (NTKR) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. The presence of this kinase leads to cell differentiation and may play a role in specifying sensory neuron subtypes. Mutations in this gene have been associated with congenital insensitivity to pain, anhidrosis, self-mutilating behavior, cognitive disability and cancer. Alternate transcriptional splice variants of this gene have been found, but only three have been characterized to date.
| Full Name | neurotrophic receptor tyrosine kinase 1 |
| Gene ID | Human: 4914 Mouse: 18211 Rat: 59109 Monkey: 719670 |
| UniProt ID | Human: P04629 Mouse: Q3UFB7 Rat: P35739 |
| Alternative Names | MTC; TRK; TRK1; TRKA; Trk-A; p140-TrkA;high affinity nerve growth factor receptor;Oncogene TRK;TRK1-transforming tyrosine kinase protein;gp140trk;neurotrophic tyrosine kinase, receptor, type 1;tropomyosin-related kinase A;tyrosine kinase receptor A |
Product List
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Magic™ Human NTRK1 & LMNA (A608D) BaF3 Cell Line
[CAT#: S01YF-1222-KX758]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: NTRK1 & LMNA (A608D) Target Family: Kinases/Enzyme Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: BaF3 Assay Types: Drug screening and biological assays
Magic™ Human NTRK1 & LMNA (F589L) BaF3 Cell Line
[CAT#: S01YF-1222-KX827]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: NTRK1 & LMNA (F589L) Target Family: Kinases/Enzyme Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: BaF3 Assay Types: Drug screening and biological assays
Magic™ Human NTRK1 & LMNA (G595R) BaF3 Cell Line
[CAT#: S01YF-1222-KX828]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: NTRK1 & LMNA (G595R) Target Family: Kinases/Enzyme Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: BaF3 Assay Types: Drug screening and biological assays
Magic™ Human NTRK1 & LMNA (G595R, F589L) BaF3 Cell Line
[CAT#: S01YF-1222-KX718]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: NTRK1 & LMNA (G595R, F589L) Target Family: Kinases/Enzyme Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: BaF3 Assay Types: Drug screening and biological assays
Magic™ Human NTRK1 & LMNA (G667A) BaF3 Cell Line
[CAT#: S01YF-1222-KX814]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: NTRK1 & LMNA (G667A) Target Family: Kinases/Enzyme Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: BaF3 Assay Types: Drug screening and biological assays
Magic™ Human NTRK1 & LMNA (G667C) BaF3 Cell Line
[CAT#: S01YF-1222-KX825]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: NTRK1 & LMNA (G667C) Target Family: Kinases/Enzyme Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: BaF3 Assay Types: Drug screening and biological assays
Magic™ Human NTRK1 & LMNA (G667S) BaF3 Cell Line
[CAT#: S01YF-1222-KX815]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: NTRK1 & LMNA (G667S) Target Family: Kinases/Enzyme Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: BaF3 Assay Types: Drug screening and biological assays
Magic™ Human NTRK1 & LMNA (V573M) BaF3 Cell Line
[CAT#: S01YF-1222-KX818]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: NTRK1 & LMNA (V573M) Target Family: Kinases/Enzyme Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: BaF3 Assay Types: Drug screening and biological assays
Magic™ Human NTRK1 & LMNA BaF3 Cell Line
[CAT#: S01YF-1222-KX821]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: NTRK1 & LMNA Target Family: Kinases/Enzyme Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: BaF3 Assay Types: Drug screening and biological assays
Magic™ Human NTRK1 BaF3 Cell Line
[CAT#: S01YF-1222-KX833]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: NTRK1 Target Family: Kinases/Enzyme Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: BaF3 Assay Types: Drug screening and biological assays
Magic™ Human NTRK1 CHO-K1 Cell Line
[CAT#: S01YF-0123-KX307]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: NTRK1 Target Family: Kinases/Enzyme Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: CHO-K1 Assay Types: Drug screening and biological assays
Magic™ Human TFG & NTRK1 BaF3 Cell Line
[CAT#: S01YF-0324-KX214]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: TFG & NTRK1 Target Family: Kinases/Enzyme Target Protein Species: Human Host Cell Type: BaF3 Assay Types: Functional assay and biological assay
Magic™ Human TPM3 & NTRK1 (F589L) BaF3 Cell Line
[CAT#: S01YF-0324-KX215]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: TPM3 & NTRK1 (F589L) Target Family: Kinases/Enzyme Target Protein Species: Human Host Cell Type: BaF3 Assay Types: Functional assay and biological assay
Magic™ Human TPM3 & NTRK1 (G595R) BaF3 Cell Line
[CAT#: S01YF-0324-KX216]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: TPM3 & NTRK1 (G595R) Target Family: Kinases/Enzyme Target Protein Species: Human Host Cell Type: BaF3 Assay Types: Functional assay and biological assay
Magic™ Human TPM3 & NTRK1 (G667C) BaF3 Cell Line
[CAT#: S01YF-0324-KX217]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: TPM3 & NTRK1 (G667C) Target Family: Kinases/Enzyme Target Protein Species: Human Host Cell Type: BaF3 Assay Types: Functional assay and biological assay
Magic™ Human TPM3 & NTRK1 (V573M) BaF3 Cell Line
[CAT#: S01YF-0324-KX218]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: TPM3 & NTRK1 (V573M) Target Family: Kinases/Enzyme Target Protein Species: Human Host Cell Type: BaF3 Assay Types: Functional assay and biological assay
Magic™ Human TPM3 & NTRK1 BaF3 Cell Line
[CAT#: S01YF-0324-KX219]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: TPM3 & NTRK1 Target Family: Kinases/Enzyme Target Protein Species: Human Host Cell Type: BaF3 Assay Types: Functional assay and biological assay
Magic™ Rat FLAG tagged NTRK1 & pGL4.30 CHO-K1 Cell Line, Calcium flux assay
[CAT#: S01YF-1022-KX636]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: NTRK1; pGL4.30 Target Family: Receptor Tyrosine Kinases Target Protein Species: Rat Protein Tag: FLAG-tag at N-terminus Host Cell Type: CHO-K1 Assay Types: Calcium flux assay
mProX™ Human NTRK1 Stable Cell Line
[CAT#: S01YF-1023-PY117]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Family: Kinases/Enzyme Target Protein Species: Human Host Cell Type: HEK293;CHO-K1;PANC-1;MDA-MB-231
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