Human NTRK1 Membrane Protein In Vitro Transcription (IVT) Plasmid
[CAT#: S01YF-1124-KX1118]
- Product Category:
- Membrane Protein Tools
- Subcategory:
- Membrane Protein Plasmids
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Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
Product Information
Product Overview
This product is a made-to-order plasmid encoding human NTRK1 for In Vitro Transcription.
Target Protein
NTRK1
Target Protein Species
Human
Target Classification
Kinases/Enzyme
Target Research Area
Cancer Research; CNS Research
Related Diseases
Insensitivity To Pain; Thyroid Carcinoma
Target Family
Kinases/Enzyme
Vector
pIVT
Vector Type
In Vitro Transcription (IVT) Vector
Note
Resistance
KanR
Growth Temperature
37°C
Relevant Promoters
T7
Mutation
Based on specific requirements
Expressed Tags
Based on specific requirements (Flag, StrepII, His, etc.)
Product Properties
Applications
In Vitro Transcription
Shipping
Blue Ice
Storage
Aliquot and store at -20°C for long term.
Target
Full Name
Neurotrophic receptor tyrosine kinase 1
Introduction
This gene encodes a member of the neurotrophic tyrosine kinase receptor (NTKR) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. The presence of this kinase leads to cell differentiation and may play a role in specifying sensory neuron subtypes. Mutations in this gene have been associated with congenital insensitivity to pain, anhidrosis, self-mutilating behavior, cognitive disability and cancer. Alternate transcriptional splice variants of this gene have been found, but only three have been characterized to date.
Alternative Names
NTRK1; MTC; TRK; TRK1; TRKA; Trk-A; p140-TrkA; high affinity nerve growth factor receptor; Oncogene TRK; TRK1-transforming tyrosine kinase protein; gp140trk; neurotrophic tyrosine kinase, receptor, type 1; tropomyosin-related kinase A; tyrosine kinase receptor A; Neurotrophic receptor tyrosine kinase 1
Gene ID
UniProt ID
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