Human NTRK1 Membrane Protein In Vitro Transcription (IVT) mRNA
[CAT#: S01YF-1124-KX198]
- Product Category:
- Membrane Protein Tools
- Subcategory:
- Membrane Protein mRNA
Certificate of Analysis Lookup
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Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
Product Information
Product Overview
This product is a made-to-order IVT mRNA encoding human NTRK1.
Target Protein
NTRK1
Target Protein Species
Human
Target Classificationp
Kinases/Enzyme
Target Research Area
Cancer Research; CNS Research
Related Diseases
Insensitivity To Pain; Thyroid Carcinoma
Target Family
Kinases/Enzyme
RNA Type
IVT mRNA
Nucleoside Modification Method
m1Ψ; m5C or specific requirements
Cap
Cap 0; Cap 1 or specific requirements
PolyA Tail (nt)
30 nt; 80 nt; 120 nt or specific requirements
5' UTR
Human globin alpha; 5' UTR seq can be modified according to the specific requirements
Promoter
T7
Tag
Based on specific requirements
Fluorescent Markers
Based on specific requirements
Formation
In Vitro Transcription (IVT) mRNA
Quality Control
OD260/280 (~1.90-2.50)
PASS
Agarose Gel Mobility
PASS
Sequence and Enzyme Digestion
PASS
Product Properties
Application
Drug discovery research and pre-clinical studies
Shipping
Dry Ice
Storage
Aliquot and store at -20°C for long term.
Target
Full Name
Neurotrophic receptor tyrosine kinase 1
Introduction
This gene encodes a member of the neurotrophic tyrosine kinase receptor (NTKR) family. This kinase is a membrane-bound receptor that, upon neurotrophin binding, phosphorylates itself and members of the MAPK pathway. The presence of this kinase leads to cell differentiation and may play a role in specifying sensory neuron subtypes. Mutations in this gene have been associated with congenital insensitivity to pain, anhidrosis, self-mutilating behavior, cognitive disability and cancer. Alternate transcriptional splice variants of this gene have been found, but only three have been characterized to date.
Alternative Names
NTRK1; MTC; TRK; TRK1; TRKA; Trk-A; p140-TrkA; high affinity nerve growth factor receptor; Oncogene TRK; TRK1-transforming tyrosine kinase protein; gp140trk; neurotrophic tyrosine kinase, receptor, type 1; tropomyosin-related kinase A; tyrosine kinase receptor A; Neurotrophic receptor tyrosine kinase 1
Gene ID
UniProt ID
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