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GHRH

A member of the glucagon family of proteins is encoded by this gene. The mature factor, known as somatoliberin, is created by cleaving the encoded preproprotein in the hypothalamus, where it functions to promote the release of growth hormone from the pituitary gland. Numerous tumor types have different somatoliberin receptors that can be inhibited by antagonists by binding to these receptors. Dwarfism is caused by mutations in this gene, whereas gigantism is caused by oversecretion of the protein it encodes.

Full Name Growth hormone releasing hormone
Gene ID Human: 2691
Mouse: 14601
Rat: 29446
Monkey: 701284
UniProt ID Human: P01286
Mouse: P16043
Rat: P09916
Monkey: G7PGF8
Alternative Names GRF; INN; GHRF; somatoliberin; growth hormone releasing factor; sermorelin; somatocrinin; somatorelin

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Product Category:
Membrane Protein Stable Cell Lines
Target Protein: GHRHR Target Family: Glucagon Target Protein Species: Human Protein Tag: FLAG-tag at N-terminus Host Cell Type: HEK293T Assay Types: cAMP assay
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: GHRH Target Family: Glucagon Family Target Protein Species: Rat Host Cell Type: Neuron;CHO-K1;HEK293
Product Category:
Membrane Protein Stable Cell Lines
Target Protein: GHRHR Target Family: Growth Hormone Releasing Hormone Receptor Family Target Protein Species: Human Host Cell Type: CHO-K1; HEK293
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