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  • mProX™ Human GHRH Stable Cell Line

    [CAT#: S01YF-0923-PY80]
    Product Category:
    Membrane Protein Stable Cell Lines
    Subcategory:
    GPCR Cell Lines

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    Host Cell Type:
    Membrane Protein Engineering:
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    Product Information

    Target Protein
    GHRH
    Target Family
    Glucagon Family
    Target Protein Species
    Rat
    Host Cell Type
    Neuron;CHO-K1;HEK293
    Target Classification
    GPCR Cell Lines
    Target Research Area
    CNS Research;Cancer Research
    Related Diseases
    Acromegaly;Gangliocytoma
    Gene ID
    Rat: 29446
    UniProt ID
    Rat: P09916

    Product Properties

    Biosafety Level
    Level 1
    Activity
    Yes
    Quantity
    10⁶ cells per vial
    Applications
    Growth hormone-releasing hormone (GHRH) has been extensively studied for its role in various physiological and pathological processes. GHRH antagonists have been identified as potential therapeutic agents for severe respiratory abnormalities, such as Acute Respiratory Distress Syndrome (ARDS). Moreover, GHRH's involvement in the growth of malignant pleural mesothelioma suggests its potential as a therapeutic target for this type of cancer. Additionally, the protective role of P53 against inflammation and cancer emphasizes the beneficial effects of GHRH antagonists in various human diseases. These findings highlight the multifaceted role of GHRH in health and disease, emphasizing its significance in therapeutic interventions.

    Protocols

    Please visit our protocols page.

    Customer Reviews

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    FAQ

    chat Kathleen (Verified Customer)

    What is the significance of growth hormone secretagogues in the diagnosis or treatment of GH deficiency? Oct 08 2022

    chat Patrick Liam (Creative Biolabs Scientific Support)

    Growth hormone secretagogues have been studied to assess their safety and efficacy for the diagnosis and/or treatment of GH deficiency in humans. Oct 08 2022

    chat Patricia (Verified Customer)

    How does the somatotrope GHRH/GH/IGF-1 axis influence immunoregulation and immunosenescence? Dec 21 2022

    chat Patrick Liam (Creative Biolabs Scientific Support)

    The somatotrope axis components have been found to be expressed in cells of both the innate and adaptive immune systems. Some clinical studies have suggested potential benefits of short-term GH treatment in acute immunodeficiencies, highlighting the importance of GH supplementation in adult GH deficiency. Dec 21 2022
    Please note: All products are "FOR RESEARCH USE ONLY. NOT FOR USE IN DIAGNOSTIC OR CLINICAL PROCEDURES" For licensing inquiries, please contact
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