CTLA4
This gene, which belongs to the immunoglobulin superfamily, produces a protein that sends T cells an inhibitory signal. The protein has a cytoplasmic tail, a transmembrane domain, and a V domain. Different isoforms are encoded by alternative transcriptional splice variants, which have been described. The soluble isoform performs as a monomer, but the membrane-bound isoform behaves as a homodimer joined by a disulfide bond. Insulin-dependent diabetic mellitus, Graves disease, Hashimoto thyroiditis, celiac disease, systemic lupus erythematosus, thyroid-associated orbitopathy, and other autoimmune illnesses have all been linked to mutations in this gene.
| Full Name | Cytotoxic T-lymphocyte associated protein 4 |
| Gene ID | Human: 1493 Mouse: 12477 Rat: 63835 Monkey: 705673 |
| UniProt ID | Human: P16410 Mouse: P09793 Rat: G3V7D2 Monkey: Q9BDC4 |
| Alternative Names | CTLA4; CD; GSE; GRD4; ALPS5; CD152; CTLA-4; IDDM12; CELIAC3; cytotoxic T-lymphocyte protein 4celiac disease 3; cytotoxic T lymphocyte associated antigen 4 short spliced form; cytotoxic T-lymphocyte-associated serine esterase-4; insulin-dependent diabetes mellitus 12; ligand and transmembrane spliced cytotoxic T lymphocyte associated antigen 4; Cytotoxic T-lymphocyte associated protein 4 |
Product List
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Magic™ Cyno CTLA4 (delta23) HEK293T Cell Line
[CAT#: S01YF-0123-KX14]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CTLA4 (delta23) Target Family: Immune Checkpoint Target Protein Species: Cyno Protein Tag: Tag-free Host Cell Type: HEK293T Assay Types: Drug screening and biological assays
Magic™ Cyno CTLA4 HEK293T Cell Line
[CAT#: S01YF-0123-KX196]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CTLA4 Target Family: Immune Checkpoint Target Protein Species: Cyno Protein Tag: Tag-free Host Cell Type: HEK293T Assay Types: Drug screening and biological assays
Magic™ Cynomolgus CTLA4 CHO-K1 Cell Line, Binding assay
[CAT#: S01YF-1022-KX152]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CTLA4 Target Family: Immune Checkpoint Target Protein Species: Cynomolgus Protein Tag: Tag-free Host Cell Type: CHO-K1 Assay Types: Binding assay
Magic™ Human CTLA4 (delta23) CHO-K1 Cell Line
[CAT#: S01YF-0123-KX15]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CTLA4 (delta23) Target Family: Immune Checkpoint Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: CHO-K1 Assay Types: Drug screening and biological assays
Magic™ Human CTLA4 (delta23) HEK293 Cell Line
[CAT#: S01YF-0123-KX81]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CTLA4 (delta23) Target Family: Immune Checkpoint Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: HEK293 Assay Types: Drug screening and biological assays
Magic™ Human CTLA4 CHO-K1 Cell Line
[CAT#: S01YF-0123-KX197]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CTLA4 Target Family: Immune Checkpoint Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: CHO-K1 Assay Types: Drug screening and biological assays
Magic™ Human CTLA4 CHO-K1 Cell Line, Binding assay
[CAT#: S01YF-1022-KX150]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CTLA4 Target Family: Immune Checkpoint Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: CHO-K1 Assay Types: Binding assay
Magic™ Human CTLA4 HEK293T Cell Line
[CAT#: S01YF-0123-KX343]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CTLA4 Target Family: Immune Checkpoint Target Protein Species: Human Protein Tag: Tag-free Host Cell Type: HEK293T Assay Types: Drug screening and biological assays
Magic™ Human CTLA4 Jurkat Cell Line, Drug screening assay
[CAT#: S01YF-0822-KX262]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CTLA4 Target Family: IgSF (immune inhibitory receptor) Target Protein Species: Human Protein Tag: Enzyme tag Host Cell Type: Jurkat Assay Types: Drug screening assay
Magic™ Mouse CTLA4 CHO-K1 Cell Line, Binding assay
[CAT#: S01YF-1022-KX151]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CTLA4 Target Family: Immune Checkpoint Target Protein Species: Mouse Protein Tag: Tag-free Host Cell Type: CHO-K1 Assay Types: Binding assay
Magic™ Mouse CTLA4 HEK293T Cell Line
[CAT#: S01YF-0123-KX199]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CTLA4 Target Family: Immune Checkpoint Target Protein Species: Mouse Protein Tag: Tag-free Host Cell Type: HEK293T Assay Types: Drug screening and biological assays
mProX™ Human CTLA4 Stable Cell Line
[CAT#: S01YF-1023-PY167]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Family: Immune Checkpoint Target Protein Species: Human Host Cell Type: HEK293;CHO-K1;H22 Assay Types: Biological assays
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