CFTR
An ATP-binding cassette (ABC) transporter superfamily member is encoded by this gene. The encoded protein regulates ion and water secretion and absorption in epithelial tissues and, unlike other members of this protein family, acts as a chloride channel. The cycles of ATP binding by the nucleotide-binding domains, regulatory domain phosphorylation, and ATP hydrolysis are what cause channel activation. Cystic fibrosis, the most prevalent deadly genetic illness among people of Northern European origin, is brought on by mutations in this gene.
| Full Name | CF transmembrane conductance regulator |
| Gene ID | Human: 1080 Mouse: 12638 Rat: 24255 Monkey: 574346 |
| UniProt ID | Human: Q20BH0 Mouse: P26361 Rat: P34158 Monkey: Q00553 |
| Alternative Names | CF; MRP7; ABC35; ABCC7; CFTR/MRP; TNR-CFTR; dJ760C5.1; cystic fibrosis transmembrane conductance regulator; cAMP-dependent chloride channel; channel conductance-controlling ATPase; cystic fibrosis transmembrane conductance regulating; cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7); CFTR; CF transmembrane conductance regulator |
Product List
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Human CFTR Membrane Protein Bacterial Expression Plasmid
[CAT#: S01YF-1124-KX719]
- Product Category:
- Membrane Protein Tools
- Target Protein: CFTR Target Family: Chloride, Ligand-Gated Vector: pBE Vector Type: Bacterial Expression Vector
Human CFTR Membrane Protein In Vitro Transcription (IVT) mRNA
[CAT#: S01YF-1124-KX144]
- Product Category:
- Membrane Protein Tools
- Target Protein: CFTR Target Family: Chloride, Ligand-Gated RNA Type: IVT mRNA Formation: In Vitro Transcription (IVT) mRNA
Human CFTR Membrane Protein In Vitro Transcription (IVT) Plasmid
[CAT#: S01YF-1124-KX1064]
- Product Category:
- Membrane Protein Tools
- Target Protein: CFTR Target Family: Chloride, Ligand-Gated Vector: pIVT Vector Type: In Vitro Transcription (IVT) Vector
Human CFTR Membrane Protein Insect Expression Plasmid
[CAT#: S01YF-1124-KX489]
- Product Category:
- Membrane Protein Tools
- Target Protein: CFTR Target Family: Chloride, Ligand-Gated Vector: pIE Vector Type: Insect Expression Vector
Human CFTR Membrane Protein Lentiviral Expression Plasmid
[CAT#: S01YF-1124-KX834]
- Product Category:
- Membrane Protein Tools
- Target Protein: CFTR Target Family: Chloride, Ligand-Gated Vector: pLV Vector Type: Lentiviral Expression Vector
Human CFTR Membrane Protein Lentivirus
[CAT#: S01YF-1124-KX29]
- Product Category:
- Membrane Protein Tools
- Target Protein: CFTR Target Family: Chloride, Ligand-Gated
Human CFTR Membrane Protein LNP Encapsulation mRNA
[CAT#: S01YF-1124-KX259]
- Product Category:
- Membrane Protein Tools
- Target Protein: CFTR Target Family: Chloride, Ligand-Gated RNA Type: LNP-mRNA Formation: LNP Encapsulation mRNA
Human CFTR Membrane Protein Mammalian Transient Expression Plasmid
[CAT#: S01YF-1124-KX374]
- Product Category:
- Membrane Protein Tools
- Target Protein: CFTR Target Family: Chloride, Ligand-Gated Vector: pME Vector Type: Mammalian Transient Expression Vector
Human CFTR Membrane Protein Retroviral Expression Plasmid
[CAT#: S01YF-1124-KX949]
- Product Category:
- Membrane Protein Tools
- Target Protein: CFTR Target Family: Chloride, Ligand-Gated Vector: pRV Vector Type: Retroviral Expression Vector
Human CFTR Membrane Protein Yeast Expression Plasmid
[CAT#: S01YF-1124-KX604]
- Product Category:
- Membrane Protein Tools
- Target Protein: CFTR Target Family: Chloride, Ligand-Gated Vector: pYE Vector Type: Yeast Expression Vector
mProX™ Human CFTR Stable Cell Line
[CAT#: S01YF-1123-KX83]
- Product Category:
- Membrane Protein Stable Cell Lines
- Target Protein: CFTR Target Family: Cystic Fibrosis Transmembrane Conductance Regulator Target Protein Species: Human Host Cell Type: A2780; SKOV3; CHO-K1; HEK293
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