Human CFTR Membrane Protein Bacterial Expression Plasmid
[CAT#: S01YF-1124-KX719]
- Product Category:
- Membrane Protein Tools
- Subcategory:
- Membrane Protein Plasmids
Certificate of Analysis Lookup
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
To download a Certificate of Analysis, please enter a lot number in the search box below. Note: Certificate of Analysis not available for kit components.
Lot Number
Product Information
Product Overview
This product is a made-to-order plasmid encoding human CFTR for Protein Expression.
Target Protein
CFTR
Target Protein Species
Human
Target Classification
Ion Channel
Target Research Area
Reproductive Research
Related Diseases
Cystic Fibrosis; Vas Deferens, Congenital Bilateral Aplasia Of
Target Family
Chloride, Ligand-Gated
Vector
pBE
Vector Type
Bacterial Expression Vector
Note
Resistance
KanR
Growth Temperature
37°C
Relevant Promoters
Lac, T7
Mutation
Based on specific requirements
Expressed Tags
Based on specific requirements (Flag, StrepII, His, etc.)
Product Properties
Applications
Protein Expression
Shipping
Blue Ice
Storage
Aliquot and store at -20°C for long term.
Target
Full Name
CF transmembrane conductance regulator
Introduction
This gene encodes a member of the ATP-binding cassette (ABC) transporter superfamily. The encoded protein functions as a chloride channel, making it unique among members of this protein family, and controls ion and water secretion and absorption in epithelial tissues. Channel activation is mediated by cycles of regulatory domain phosphorylation, ATP-binding by the nucleotide-binding domains, and ATP hydrolysis. Mutations in this gene cause cystic fibrosis, the most common lethal genetic disorder in populations of Northern European descent. The most frequently occurring mutation in cystic fibrosis, DeltaF508, results in impaired folding and trafficking of the encoded protein. Multiple pseudogenes have been identified in the human genome.
Alternative Names
CF; MRP7; ABC35; ABCC7; CFTR/MRP; TNR-CFTR; dJ760C5.1; cystic fibrosis transmembrane conductance regulator; cAMP-dependent chloride channel; channel conductance-controlling ATPase; cystic fibrosis transmembrane conductance regulating; cystic fibrosis transmembrane conductance regulator (ATP-binding cassette sub-family C, member 7); CFTR; CF transmembrane conductance regulator
Gene ID
UniProt ID
Customer Reviews
There are currently no Customer reviews or questions for Human CFTR Membrane Protein Bacterial Expression Plasmid (S01YF-1124-KX719). Click the button above to contact us or submit your feedback about this product.
